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Granulocyte Macrophage-Colony Stimulating Factor, canine recombinant

ART NR.: 97369.1 (1 mg)
97369.2 (2 µg)
97369.10 (10 µg)

Hersteller: Biomol GmbH

Datenblatt

Anwendungen: Cell Culture

Exprimiert in: E.coli

MW: 14.200 D

Reinheit: >96%

Format: purified

UniProt ID: P48749
Suche mit UniProt ID

Schlagworte: CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim, MGC131935, MGC138897

1 mg

2 µg

69 €

10 µg

179 €

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Bemerkungen: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes (By similarity). (www.uniprot.org) Recombinant canine GMCSF produced in E.coli is a single, non-glycosylated, polypeptide chain containing 128 amino acids and having a molecular mass of 14.2 kDa. GM-CSF is purified by proprietary chromatographic techniques. GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

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