- Search results for Cay10010750-1
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11 products were found matching "Cay10010750-1"!
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Item number: Cay10010501-10
Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) is an inhibitor of Ras-mediated signaling that functions by dislodging Ras from the cell membrane thereby rendering it susceptible to proteolytic degradation. FTS...
Keywords: | FTS, Salirasib, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-benzoic acid |
Application: | Ras inhibitor |
CAS | 162520-00-5 |
MW: | 358.5 D |
From 54.00€
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Item number: Cay10010-50
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: | PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 14152-28-4 |
MW: | 336.5 D |
From 48.00€
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Item number: Cay10010517-50
2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2,3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of...
Keywords: | 1-(4-chlorobenzoyl)-4-[[4-(4,5-dihydro-2-oxazolyl)phenyl]methylene]-piperidine |
Application: | OSC inhibitor |
CAS | 156635-05-1 |
MW: | 380.9 D |
From 60.00€
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Item number: Cay10010075-1
Formulation: A solution of alkaline phosphatase. Origin: Animal/Bovine.
Application: | Kit component |
36.00€
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Item number: Cay10010706-50
(-)-Deguelin is a rotenoid that has been found in T. vogelii and has diverse biological activities. It inhibits mitochondrial complex I, also known as NADH dehydrogenase, activity in bovine heart electron transport particles and phorbol 12-myristate 13-acetate-induced ornithine decarboxylase (ODC) activity in MCF-7...
Keywords: | (-)-cis-Deguelin, 13,13aS-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-[1]benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aS)-one |
Application: | Chemopreventive effector |
CAS | 522-17-8 |
MW: | 394.4 D |
From 70.00€
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Item number: Cay10010785-50
(±)-Lisofylline (LSF) is a potent anti-inflammatory agent in which only the (-) optical isomer is biologically active. LSF inhibits the generation of phosphatidic acid (IC50 = 0.6 µM) from cytokine-activated lysophosphatidic acyl transferase (LPAAT), which has been shown to protect mice from endotoxic shock. LSF...
Keywords: | BL 194, CT-1501R, LSF, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione |
Application: | Phosphatidic acid generation inhibitor |
CAS | 6493-06-7 |
MW: | 280.3 D |
From 98.00€
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Item number: Cay10010570-1
Risperidone-d5 is intended for use as an internal standard for the quantification of risperidone (Cay-13629) by GC- or LC-MS. Risperidone is an atypical antipsychotic that binds to dopamine D2 receptors (Ki = 3 nM) and the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 0.12 nM). It also binds to dopamine D4, alpha1-...
Keywords: | 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-1,1,2,2-d4]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrim... |
Application: | GC-MS, LC-MS, Internal standard |
CAS | 1020719-76-9 |
MW: | 414.5 D |
From 163.00€
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Item number: Cay10010337-50
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt, hydrate |
Application: | Hydroxymethylglutaryl-coenzyme A reductase inhibitor |
MW: | 410.5 D |
From 35.00€
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Item number: Cay10010907-50
Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PF-622 is a potent, time-dependent, irreversible FAAH inhibitor with IC50 values of 0.99 and 0.033 µM when preincubated with human recombinant FAAH for 5 and 60 minutes,...
Keywords: | N-phenyl-4-(2-quinolinylmethyl)-1-piperazinecarboxamide |
Application: | FAAH inhibitor |
CAS | 898235-65-9 |
MW: | 346.4 D |
From 34.00€
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Item number: Cay10010487-50
Lubiprostone is an activator of chloride channel protein 2 (ClC-2) and a bicyclic derivative of prostaglandin E1 (PGE1, Cay-13010). It induces chloride currents in HEK293 cells expressing recombinant human ClC-2 (EC50 = ~17 nM), but not CFTR, chloride channels. Lubiprostone (1 µM) induces short-circuit currents, a...
Keywords: | RU-0211, SPI-0211, 16,16-difluoro-11alpha-hydroxy-9,15-dioxo-prostan-1-oic acid |
Application: | ClC-2 activator |
CAS | 136790-76-6 |
MW: | 390.5 D |
From 84.00€
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Item number: Cay10010175-10
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of PI at the three position of the inositol ring to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kgamma is a class 1B PI3K that is composed of a p110 catalytic subunit and a p101 or p84 regulatory subunit, whereas...
Keywords: | 5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione |
Application: | PI3Kgamma inhibitor |
CAS | 648449-76-7 |
MW: | 285.2 D |
From 35.00€
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