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Bromodomain

Info

BRD is not only an abbreviation of Bundesrepublik Deutschland, but also of Bromodomain.
A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. The domain itself adopts an all-? protein fold, a bundle of four alpha helices. [1]

Bromodomain Assay Kits and Kit Components



 Cat #   Size   Product Name 
 BPS-33001    10 ml   3x BRD Assay Buffer 
 BPS-33002    10 ml   3x BRD Detection Buffer 
 BPS-32513    384 reactions   BRD3 (BD1) Inhibitor Screening Assay Kit 
 BPS-32523    384 reactions   BRD3 (BD2) Inhibitor Screening Assay Kit 
 BPS-32514    384 reactions   BRD4 (BD1) Inhibitor Screening Assay Kit 
 BPS-32504    384 reactions   BRD4 (BD1/BD2) Inhibitor Screening Assay Kit 
 BPS-32524    384 reactions   BRD4 (BD2) Inhibitor Screening Assay Kitt 


Bromodomain Proteins


 Cat #   Size   Product Name 
 BPS-31109   100 µg   ATAD2 (981-1108), His-tag 
 BPS-31113   100 µg   BAZ2B (2054 – 2168) 
 BPS-31011   100 µg   BRD1 (561-668), GST-tag 
 BPS-31010   100 µg   BRD1 (561-668), His-tag 
 BPS-31023   100 µg   BRD2 (339-459), GST-tag 
 BPS-31020   100 µg   BRD2 (339-459), His-tag 
 BPS-31021   100 µg   BRD2 (65-187), GST-tag 
 BPS-31022   100 µg   BRD2 (65-187), His-tag 
 BPS-31024   100 µg   BRD2, BD1 and BD2 (65-459), GST-tag 
 BPS-31032   100 µg   BRD3 (29-145), GST-tag 
 BPS-31030   100 µg   BRD3 (29-145), His-tag 
 BPS-31033   100 µg   BRD3 (306-417), GST-tag 
 BPS-31031   100 µg   BRD3 (306-417), His-tag 
 BPS-31041   100 µg   BRD4 (342-460), GST-tag 
 BPS-31043   100 µg   BRD4 (342-460), His-tag 
 BPS-31040   100 µg   BRD4 (49-170), GST-tag 
 BPS-31042   100 µg   BRD4 (49-170), His-tag 
 BPS-31090   100 µg   BRD9 (135-242), His-tag 
 BPS-31108   100 µg   BRDT (22-138), GST-tag 
 BPS-31101   100 µg   BRDT (22-138), His-tag 
 BPS-31100   100 µg   BRDT (257-382), His-tag 
 BPS-31102   100 µg   BRG1 (1480-1603), His-tag 
 BPS-31112   100 µg   BRPF1 (627-746), His-tag 
 BPS-31114   100 µg   GCN5 (727 - 837), His-tag 
 BPS-31111   100 µg   SMARCA2 (1375-1511), His-tag 
 BPS-31110   100 µg   TAF1 (1519-1651), His-tag 
 BPS-31105   100 µg   TAF1L (1398-1516), GST-tag 
 BPS-31103   100 µg   TAF1L (1398-1516), His-tag 
 BPS-31107   100 µg   TAF1L (1398-1649), GST-tag 
 BPS-31106   100 µg   TAF1L (1517-1649), GST-tag 
 BPS-31104   100 µg   TAF1L (1517-1649), His-tag 
 BPS-31116   100 µg   TRIM24 (896-1014) 
 BPS-31115   100 µg   WDR9 (1308 – 1436) 


Bromodomain Ligands



 Cat #   Size   Product Name 
 BPS-33000   500 µL   BET Bromodomain Ligand 


Bromodomain Inhibitor



 Cat #   Size   Product Name 
 BPS-27401/2/0   1/5/10 mg   (+)-JQ1 Bromodomain Inhibitor 


Listing of Protein Containing Bromodomains


About 41 human proteins contain one or several bromodomains [2]:

References


1 http://en.wikipedia.org/wiki/Bromodomain
2 The Uniprot Consortium

Deacetylases: HDACs, Sirtuins


Native Glycosylation of Recombinant Human ProteinsSelective Protease Activity Imaging in 3DCONDA Chromogenic Media Special Offer

StressMarq Antibody Trial ProgramThe Importance of Internal StandardsTrueBlot for Optimum WB after IP alle Treffer anzeigen (389 INFOS)


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