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Anti-phospho-4E Binding Protein 1 (Ser112) (Eukaryotic Translation Initiation Factor 4E Binding Prot
Anti-phospho-4E Binding Protein 1 (Ser112) (Eukaryotic...

Item number: 0004-21A.20

Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the eIF4E translation initiation factor. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation (1). Both the PI3 kinase/Akt pathway and FRAP/mTOR...
Keywords: Anti-phospho-4E-BP1, Anti-phospho-PHAS-I, Anti-phospho-EIF4EBP1, Anti-phospho-eIF4E-binding protein 1,...
Application: FC, IF, IHC, IP, WB
Host: Rabbit
Species reactivity: human, monkey, mouse, rat
From 395.00€ *
Review
Anti-phospho-4E Binding Protein-1 (Ser65) (4E-BP1, PHAS-1)
Anti-phospho-4E Binding Protein-1 (Ser65) (4E-BP1, PHAS-1)

Item number: 0004-20.100

4E-BP1 (also known as PHAS-1) normally binds eIF4E, inhibiting cap-dependent translation. Hyperphosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation. The PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1. 4E-BP1 is phosphorylated in vivo on multiple residues, phosphorylation...
Application: ELISA, IP, WB
Host: Rabbit
Species reactivity: human, monkey, mouse, rat
711.00€ *
Review