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May be involved in DNA repair.
Immunogen: synthetic peptide. The epitope recognized by IHC-​00572 maps to a region between residue 575 and the C-​terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Rabbit
> sec. Ab
Pab
Human, Mouse
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IHCErklärungen der Abkürzungen ansehen. Bethyl
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IHC-​00572 100 µl

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Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-​dependent unwinding of 5'-​terminal secondary structure and recruitment of mRNA to the ribosome.
Immunogen: synthetic peptide. The epitope recognized by IHC-​00566 maps to a region between residue 525 and 575 of human eukaryotic translation initiation factor 4 gamma, 1 using the numbering given in entry NP_886553.2 (GeneID 1981).
Rabbit
> sec. Ab
Pab
Human, Mouse
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IHCErklärungen der Abkürzungen ansehen. Bethyl
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IHC-​00566 100 µl

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Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-​mRNA. It is recruited to spliced mRNAs by a transcription-​independent mechanism. Binds to mRNA upstream of the exon-​ ... mehr
Immunogen: synthetic peptide. The epitope recognized by A302-​892A maps to a region between residue 25 and 75 of human Ally of AML-​1 and LEF-​1 using the numbering given in entry AAH52302.1 (GeneID 10189).
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified WB
IPErklärungen der Abkürzungen ansehen.
Bethyl
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A302-​892A

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100 µl

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Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-​mRNA. It is recruited to spliced mRNAs by a transcription-​independent mechanism. Binds to mRNA upstream of the exon-​ ... mehr
Immunogen: synthetic peptide. The epitope recognized by A302-​893A maps to a region between residue 75 and 125 of human Ally of AML-​1 and LEF-​1 using the numbering given in entry AAH52302.1 (GeneID 10189).
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IPErklärungen der Abkürzungen ansehen. Bethyl
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A302-​893A 100 µl

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1 each of A302-​892A and A302-​893A
Immunogen: snythetic peptide
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified WB
IPErklärungen der Abkürzungen ansehen.
Bethyl
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A311-​067A

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1 pack

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Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-​phosphate of phosphatidylinositol-​3,4,5-​trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-​kinase) pathways. Pla ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-​00567 maps to a region between residues 100 and 150 of human inositol polyphosphate phosphatase-​like 1 using the numbering given in entry NP_001558.2 (GeneID 3636).
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IHCErklärungen der Abkürzungen ansehen. Bethyl
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IHC-​00567 100 µl

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Activates Rho-​GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, and ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-​00569 maps to a region between residue 625 and 675 of human guanine nucleotide exchange factor H1 using the numbering given in entry CAH72629.1 (GeneID 9181).
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IHCErklärungen der Abkürzungen ansehen. Bethyl
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IHC-​00569 100 µl

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Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Immunogen: synthetic peptide. The epitope recognized by IHC-​00570 maps to a region between residues 825 and the C-​terminus (residue 878) using the numbering given in entry NP_057541.2 (GeneID 25865).
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IHCErklärungen der Abkürzungen ansehen. Bethyl
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IHC-​00570 100 µl

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E3 ubiquitin-​protein ligase which accepts ubiquitin from specific E2 ubiquitin-​conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-​cell receptor), BCR (B-​cell receptor) ... mehr
Immunogen: synthetic peptide. The epitope recognized by A302-​902A maps to a region between residue 450 and 500 of human Cas-​Br-​M (murine) Ecotropic Retroviral Transforming Sequence b using the numbering given in entry NP_733762.2 (GeneID 868).
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IPErklärungen der Abkürzungen ansehen. Bethyl
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A302-​902A 100 µl

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349 €
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E3 ubiquitin-​protein ligase which accepts ubiquitin from specific E2 ubiquitin-​conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-​cell receptor), BCR (B-​cell receptor) ... mehr
Immunogen: synthetic peptide. The epitope recognized by A302-​903A maps to a region between residue 932 and 982 of human Cas-​Br-​M (murine) Ecotropic Retroviral Transforming Sequence b using the numbering given in entry NP_733762.2 (GeneID 868).
Rabbit
> sec. Ab
Pab
Human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified WB
IPErklärungen der Abkürzungen ansehen.
Bethyl
Icon Datasheet
A302-​903A

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100 µl

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349 €
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