13 products were found matching "3318-1"!

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the...

KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII, IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).Formal Name:...

CP21 is an iron chelator that binds to iron in a 3:1 (ligand:iron) ratio. It is active against P. falciparum when used at concentrations of 10 and 100 µM. CP21 inhibits production of prostaglandin I2 (PGI2, Cay-18220) induced by epinephrine, arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607), or A23187...

Protein function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Lymphocyte-specific protein 1 Protein function: May play a role in mediating neutrophil activation and chemotaxis. [The UniProt Consortium]

Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone...

Formulation: A solution in ethanol.

6-O-demethyl Griseofulvin is a metabolite of the antifungal griseofulvin (Cay-19461).Formal Name: (1'S,6'R)-7-chloro-6-hydroxy-2',4-dimethoxy-6'-methyl-spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione. CAS Number: 20168-88-1. Synonyms: 6-Demethylgriseofulvin. Molecular Formula: C16H15ClO6. Formula Weight: 338.7....

HOE 33187 is a derivative of the fluorescent DNA probe Hoechst 33258 (Cay-16756). It is cytotoxic to L1210 murine skin lymphocytic leukemia cells (IC50 = 480 nM).Formal Name: 6-(4-methyl-1-piperazinyl)-2'-phenyl-2,6'-bibenzimidazole. CAS Number: 23623-08-7. Molecular Formula: C25H24N6. Formula Weight: 408.5. Purity:...

L-Azetidine-2-carboxylic acid is a non-proteinogenic amino acid derivative of L-proline that has been found in C. majalis and has diverse biological activities. It is toxic to a variety of bacteria, but the bacteria E. agglomerans and E. amnigenus metabolize it for use as a source of nitrogen....

AZD 7986 is a reversible and covalent inhibitor of dipeptidyl peptidase 1 (DPP-1), also known as cathepsin C (IC50 = 3.9 nM). It is selective for DPP-1 over cathepsins S, -L, -B, -K, -D, -E, -Z, -H, and -G (IC50s = >20 µM for all), as well as a panel of greater than 200 enzymes, receptors, ion channels, and...

Gadoleic acid is a monounsaturated fatty acid. It inhibits the dsDNA binding activity of p53 when used at a concentration of 1.2 nM. Hepatic levels of gadoleic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet and increased in rats fed a high-cholesterol diet.Formal Name: 9Z-eicosenoic...