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Pralsetinib
Pralsetinib

Item number: Cay33181-1

Pralsetinib is an inhibitor of RET (IC50s = 0.4, 0.3, 0.4, and 0.4 nM for wild-type RET, RETV804L, RETV804M, and RETM918T, respectively). It is selective for RET over VEGFR2 (IC50 = 35 nM) and a panel of 371 kinases at 300 nM. Pralsetinib also inhibits a fusion protein of coiled-coil domain-containing protein 6 with...
Keywords: BLU-667,...
Application: RET inhibitor
CAS 2097132-94-8
MW: 533.6 D
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