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AZD 4604
AZD 4604

Item number: Cay39890-10

AZD 4604 is a JAK1 inhibitor (IC50 = 0.54 nM). It is selective for JAK1 over JAK2 and JAK3 (IC50s = 686 and >10,000 nM, respectively), as well as tyrosine kinase 2 (TYK2, IC50 = 657 nM). AZD 4604 inhibits IL-4- or IL-13-induced phosphorylation of STAT6 in U937 cells (IC50s = 24 and 34 nM, respectively). In vivo, AZD...
Keywords: Londamocitinib,...
Application: JAK1 inhibitor
CAS 2241039-81-4
MW: 599.7 D
From 34.00€ *
Review
Anti-PUM1
Anti-PUM1

Item number: E-AB-64604.120

This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal...
Keywords: Anti-HsPUM, Anti-Pumilio-1, Anti-Pumilio homolog 1, PUM1 Polyclonal Antibody
Application: WB
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-Cytokeratin 17, clone KRT17/4604
Anti-Cytokeratin 17, clone KRT17/4604

Item number: NSJ-V9167-100UG

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various...
Keywords: Anti-K17, Anti-39.1, Anti-CK-17, Anti-KRT17, Anti-Keratin-17, Anti-Cytokeratin-17, Anti-Keratin, type I cytoskeletal 17,...
Application: IHC (paraffin)
Host: Mouse
Species reactivity: human
From 332.00€ *
Review
Anti-Cytokeratin 17, clone KRT17/4604
Anti-Cytokeratin 17, clone KRT17/4604

Item number: NSJ-V9167SAF-100UG

1 mg/ml in 1X PBS, BSA free, sodium azide free. Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glandssuch as mammary, sweat and...
Keywords: Anti-K17, Anti-39.1, Anti-CK-17, Anti-KRT17, Anti-Keratin-17, Anti-Cytokeratin-17, Anti-Keratin, type I cytoskeletal 17,...
Application: IHC (paraffin)
Host: Mouse
Species reactivity: human
752.00€ *
Review
UNC0642
UNC0642

Item number: Cay14604-1

The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferases G9a and G9a-like protein (GLP) can mono- or dimethylate lysine 9 on histone 3, contributing to early embryogenesis, genomic imprinting, and lymphocyte...
Keywords: 2-(4,4-difluoropiperidin-1-yl)-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Application: EHMT1 / EHMT2 inhibitor
CAS 1481677-78-4
MW: 546.7 D
From 84.00€ *
Review
INSM1, Human insulinoma-associated 1, Real Time PCR Primer Set
INSM1, Human insulinoma-associated 1, Real Time PCR...

Item number: VHPS-4604

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: IA1, INSM1, Zinc finger protein IA-1, Insulinoma-associated protein 1
Application: RNA quantification
43.00€ *
Review
Anti-GSTP1 (GST class-pi, GSTP1-1)
Anti-GSTP1 (GST class-pi, GSTP1-1)

Item number: 144604.100

Glutathione S-transferases pi, also known as GST3, present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. The GST-pi gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. The GST-pi gene is mapped to chromosome 11 .Placental...
Application: IHC, WB
Host: Rabbit
Species reactivity: human, mouse, rat
659.00€ *
Review
Recombinant Human RAP2A, Member RAS Oncogene Family
Recombinant Human RAP2A, Member RAS Oncogene Family

Item number: ABE-32-4604-10

Source : Escherichia Coli. RAP2A Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 200 amino acids (1-180 a.a.) and having a molecular mass of 22.4kDa. The RAP2A is purified by proprietary chromatographic techniques....
554.00€ *
Review