15 products were found matching "6676-1"!

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AZD 1080
AZD 1080

Item number: Cay16676-1

The two isoforms of glycogen synthase kinase 3, GSK3alpha and GSK3beta, constitutively phosphorylate and inactivate glycogen synthase, preventing glycogen synthesis. They also phosphorylate proteins that are relevant to Alzheimer's disease and osteogenesis. AZD 1080 is a potent, brain permeable inhibitor of...
Keywords: 2-hydroxy-3-[5-(4-morpholinylmethyl)-2-pyridinyl]-1H-indole-5-carbonitrile
Application: Brain permeable GSK3alpha/beta inhibitor
CAS 612487-72-6
MW: 334.4 D
From 37.00€ *
Review
Axitinib-13C-d3
Axitinib-13C-d3

Item number: Cay26676-1

Axitinib-13C-d3 is intended for use as an internal standard for the quantification of axitinib (Cay-13813) by GC- or LC-MS. Axitinib (Cay-13813) is a VEGFR inhibitor (IC50s = 1.2, 0.25, and 0.29 nM for VEGFR1, -2, and -3, respectively). It also inhibits c-Kit and PDGFRbeta (IC50s = 1.7 and 1.6 nM, respectively). It...
Keywords: AG-013736-13C-d3, (E)-N-(methyl-13C-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide
Application: GC-MS, LC-MS, quantification, internal standard, receptor tyrosine kinase inhibitor
CAS 1261432-00-1
MW: 390.5 D
From 810.00€ *
Review
ALPL Mouse
ALPL Mouse

Item number: ABE-32-6676-1

Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.Alkaline Phosphatase Liver/Bone/Kidney (Alpl) is a part of the alkaline phosphatases family which comprises 4 related alkaline phosphatases. Alpl is a membrane-bound glycosylated enzyme which is not expressed in any particular tissue. Alpl takes part...
Application: FA
Expressed in: Insect cells
Origin: mouse
From 438.00€ *
Review
Anti-VDR
Anti-VDR

Item number: E-AB-60676.120

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors....
Keywords: Anti-VDR, Anti-NR1I1, Anti-Vitamin D3 receptor, Anti-1,25-dihydroxyvitamin D3 receptor, Anti-Nuclear receptor subfamily 1...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
Anti-GSTM2
Anti-GSTM2

Item number: E-AB-64676.120

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione...
Keywords: Anti-GST4, Anti-GSTM2, Anti-GSTM2-2, EC=2.5.1.18, Anti-GST class-mu 2, Anti-Glutathione S-transferase Mu 2, GSTM2...
Application: WB, IHC, IF
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-IFNA1
Anti-IFNA1

Item number: E-AB-65676.120

The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. Protein function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an...
Keywords: Anti-IFNA1, Anti-LeIF D, Anti-IFNA13, Anti-IFN-alpha-1/13, Anti-Interferon alpha-D, Anti-Interferon alpha-1/13, IFNA1...
Application: IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
Anti-UGT1A4
Anti-UGT1A4

Item number: E-AB-67676.120

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases....
Keywords: Anti-GNT1, Anti-UGT1D, Anti-UGT1A4, Anti-UGT-1D, Anti-UGT1*4, Anti-UGT1.4, Anti-hUG-BR2, Anti-UGT1-04, Anti-UDPGT 1-4,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-CDK14
Anti-CDK14

Item number: E-AB-66376.120

CDK14 (Cyclin Dependent Kinase 14) is a Protein Coding gene. Among its related pathways are Transcriptional misregulation in cancer. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog...
Keywords: Anti-CDK14, Anti-KIAA0834, Anti-hPFTAIRE1, EC=2.7.11.22, Anti-Cyclin-dependent kinase 14, Anti-Cell division protein...
Application: WB
Host: Rabbit
Species reactivity: mouse
From 198.00€ *
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Anti-ME3
Anti-ME3

Item number: E-AB-66576.120

Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene...
Keywords: Anti-ME3, Anti-NADP-ME, EC=1.1.1.40, Anti-Malic enzyme 3, Anti-NADP-dependent malic enzyme, mitochondrial, ME3 Polyclonal...
Application: IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
Anti-FKBP1B
Anti-FKBP1B

Item number: E-AB-66786.120

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly...
Keywords: Anti-FKBP1B, Anti-FKBP-1B, Anti-Rotamase, Anti-FKBP12.6, Anti-h-FKBP-12, Anti-FKBP-12.6, EC=5.2.1.8, Anti-PPIase FKBP1B,...
Application: IHC, IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
Anti-MAD2L1
Anti-MAD2L1

Item number: E-AB-66796.120

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. Protein function: Component of the...
Keywords: Anti-MAD2, Anti-MAD2L1, Anti-HsMAD2, Anti-MAD2-like protein 1, Anti-Mitotic arrest deficient 2-like protein 1,...
Application: IHC, IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
Anti-(KO Validated) HSPB1
Anti-(KO Validated) HSPB1

Item number: E-AB-66764.120

This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important...
Keywords: Anti-HspB1, Anti-HSP27, Anti-HSPB1, Anti-SRP27, Anti-HSP 27, Anti-28 kDa heat shock protein, Anti-Heat shock 27 kDa...
Application: WB, IHC, IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 218.00€ *
Review
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