- Search results for 5438-1
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10 products were found matching "5438-1"!
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Item number: Cay21598-10
AZD 5438 is a potent inhibitor of the cyclin-dependent kinases (CDKs) 1, 2, and 9 (IC50s = 16, 6, and 20 nM, respectively). AZD 5438 also inhibits the kinase activity of Cdk5/p25 and glycogen synthase kinase 3beta (GSK3beta) (IC50s = 14 and 17 nM, respectively). AZD 5438 induces cell cycle arrest by inhibiting...
Keywords: | 4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
Application: | Cdk1 / Cdk2 / Cdk9 inhibitor |
CAS | 602306-29-6 |
MW: | 371.5 D |
From 119.00€
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Item number: E-AB-65438.120
The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. Protein function: May function as an adapter protein. Required for efficient...
Keywords: | Anti-CED6, Anti-GULP1, Anti-Protein GULP, Anti-Cell death protein 6 homolog, Anti-PTB domain adapter protein CED-6,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: Cay25438-1
Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin (Cay-81025, Cay-81025.1) by GC- or LC-MS. Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities. It inhibits nitric oxide (NO) production (IC50 = 6 µM) and...
Keywords: | (1E,4Z,6E)-5-hydroxy-1,7-bis[4-hydroxy-3-(methoxy-d3)phenyl]-1,4,6-heptatrien-3-one |
Application: | GC-MS, LC-MS, internal standard |
CAS | 1335198-02-1 |
MW: | 374.4 D |
From 109.00€
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Item number: LKT-A965121.100
Keywords: | AZD5438, MMV676604, 4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine |
Application: | Cdk1 / Cdk2 / Cdk9 inhibitor |
CAS | 602306-29-6 |
MW: | 371.45 D |
From 128.00€
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Item number: VHPS-5438
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | APT2, APT-2, LYPLA2, LPL-II, LysoPLA II, EC=3.1.2.-, Lysophospholipase II, Acyl-protein thioesterase 2 |
Application: | RNA quantification |
43.00€
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Item number: VRPS-5438
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | SCPX, Scp2, SCP-2, SCP-X, NSL-TP, SCP-chi, EC=2.3.1.176, Sterol carrier protein 2, Sterol carrier protein X, Propanoyl-CoA... |
Application: | RNA quantification |
52.00€
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Item number: 225438.100
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 531.00€
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Item number: E-AB-52438.120
UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1, MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]). Protein function: E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. [The UniProt Consortium]
Keywords: | Anti-UFC1, Anti-CGI-126, Anti-Ufm1-conjugating enzyme 1, Anti-Ubiquitin-fold modifier-conjugating enzyme 1, UFC1... |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 71.00€
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Item number: 375438.100
Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration. Source: Recombinant protein corresponding to aa1-426...
Keywords: | SOK1, SOK-1, STK25, EC=2.7.11.1, Ste20-like kinase, Serine/threonine-protein kinase 25, Ste20/oxidant stress response... |
MW: | 64,1 |
From 511.00€
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Item number: Cay35438-100
Matrix metalloproteinase-1 (MMP-1) is an endopeptidase that has a major role in tissue remodeling. It is composed of an N-terminal extracellular signal peptide, a prodomain containing a cysteine switch that interacts with the catalytic domain to regulate the proteolytic activity of MMP-1, a catalytic domain, and a...
Keywords: | CLG, MMP1, MMP-1, Fibroblast collagenase, Interstitial collagenase, Matrix metalloproteinase-1, 22 kDa interstitial... |
Application: | Active enzyme |
Expressed in: | Human cells |
Origin: | human |
MW: | 50-55 kD |
From 204.00€
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