TPR (translocated promoter region) was identified in oncogenic fusions with the kinase domains of trk, met, and raf protooncogenes. TPR has also been identified as a candidate nuclear skeletal protein that localizes to nuclear pore-associated intranuclear ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-00099 maps to a region between residue 2300 and the C-terminus (residue 2349) of human Translocated Promoter Region Protein using the numbering given in entryNP_003283.1 (GeneID 7175).
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Rabbit
> sec. Ab |
Pab |
IgG
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human, mouse
 |
antigen affinity purified |
IHC
ICC |
Bethyl
 |
IHC-00099 |
100 µl Buy Bulk |
399 €
|
NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like) functions as an E3 ubiquitin-protein ligase. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. It also prom ... mehr
Immunogen: synthetic peptide
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Rabbit
> sec. Ab |
Pab |
IgG
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human, mouse
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antigen affinity purified |
IHC |
Bethyl
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IHC-00713 |
100 µl Buy Bulk |
399 €
|
Chromosome region maintenance 1 protein homolog (CRM1) is the Ran-GTP-binding nuclear export receptor for proteins bearing a leucine rich nuclear export signal and RNAs. CRM1 also possesses a mitotic function as it localizes to kinetochores, and with Ran- ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-00139 maps to a region between residues1025 and the C-terminus (residue 1071) of human Chromosome Region Maintenance 1 (Exportin 1) using the numbering given in entry NP_003391.1 (GeneID 7514).
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Rabbit
> sec. Ab |
Pab |
IgG
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human, mouse
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antigen affinity purified |
IHC |
Bethyl
|
IHC-00139 |
100 µl Buy Bulk |
399 €
|
Filamin B is a cytoplasmic protein that functions to link cell membrane proteins to the actin cytoskeleton. Defects in Filamin B are associated with a number of diseases characterized by skeletal dysplasias and abnormalities. Alternate names for Filamin B ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-00355 maps to a region between residue 2552 and 2602 of human filamin B, beta (actin binding protein 278) using the numbering given in entry NP_001448.2 (GeneID 2317).
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Rabbit
> sec. Ab |
Pab |
IgG
|
human
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antigen affinity purified |
IHC |
Bethyl
|
IHC-00355 |
100 µl Buy Bulk |
399 €
|
Immunogen: synthetic peptide. The epitope recognized by IHC-00236 maps to a region between residue 2442 and the C-terminus (residue 2492) of human alpha thalassemia/mental retardation syndrome X-linked using the numbering given in entry NP_000480.2 (GeneID 546).
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Rabbit
> sec. Ab |
Pab |
IgG
|
human
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antigen affinity purified |
IHC |
Bethyl
|
IHC-00236 |
100 µl Buy Bulk |
399 €
|
Immunogen: The epitope recognized by IHC-00663 maps to a region between residue 359 and 409 of human UV excision repair protein RAD23 homolog using the numbering given in entry NP_002865.1 (GeneID 5887).
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Rabbit
> sec. Ab |
Pab |
|
human
|
antigen affinity purified |
IHC |
Bethyl
|
IHC-00663 |
100 µl Buy Bulk |
399 €
|
NCOA62 is an integral component of the splicesome that functions in pre-mRNA splicing. NCOA62 has also been demonstrated to function as a coactivator of the Notch transcription factor and the vitamin D nuclear receptor. Additionally, NCOA2 exhibits trans ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-00192 maps to a region between residues 450 and 500 of human Nuclear Receptor Coactivator, 62 kD (SKIIP, SKI Interacting Protein) using the numbering given in entry NP_036377.1 (GeneID 22938).
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Rabbit
> sec. Ab |
Pab |
IgG
|
human, mouse
|
antigen affinity purified |
IHC |
Bethyl
|
IHC-00192 |
100 µl Buy Bulk |
399 €
|
The protein product of the Werners syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile r ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-00407 maps to a region between residues 1400 and the C-terminus (residue 1432) of human Werner Syndrome Helicase using the numbering given in SwissProt entry Q14191 (GeneID 7486).
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Rabbit
> sec. Ab |
Pab |
IgG
|
human
|
antigen affinity purified |
IHC |
Bethyl
|
IHC-00407 |
100 µl Buy Bulk |
399 €
|
Ribosomal protein S6 kinase alpha-2 (RSK2) is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. RSK2 kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitog ... mehr
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Rabbit
> sec. Ab |
Pab |
IgG
|
|
|
IHC
IHC-IF |
Bethyl
|
IHC-00683 |
100 µl Buy Bulk |
399 €
|
SUV39H1 is a histone methyltransferase that specifically trimethylates Lys-9 of histone H3 and is important in the establishment of constitutive heterochromatin at pericentric and telomeric regions. SUV39H1 has been shown to interact with Smad5 and functi ... mehr
Immunogen: synthetic peptide. The epitope recognized by IHC-00628 maps to a region between residue 75 and 125 of human suppressor of variegation 3-9 homolog 1 using the numbering given in entry NP_003164.1 (GeneID 6839).
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Rabbit
> sec. Ab |
Pab |
IgG
|
human
|
antigen affinity purified |
IHC |
Bethyl
|
IHC-00628 |
100 µl Buy Bulk |
399 €
|
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