Anti-AKT3, clone 25F6.F6.D8

Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-301-E75S 25 µl - -

6 - 10 business days*

180.00€
200-301-E75 100 µg - -

6 - 10 business days*

698.00€
 
Protein function: AKT3 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2... more
Product information "Anti-AKT3, clone 25F6.F6.D8"
Protein function: AKT3 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase- dependent apoptosis. [The UniProt Consortium]
Keywords: Anti-AKT3, Anti-PKBG, Anti-STK-2, Anti-PKB gamma, EC=2.7.11.1, Anti-RAC-PK-gamma, Anti-Protein kinase Akt-3, Anti-Protein kinase B gamma, Anti-RAC-gamma serine/threonine-protein kinase
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-301-E75

Properties

Application: ELISA, FC, IHC, WB
Antibody Type: Monoclonal
Clone: 25F6.F6.D8
Conjugate: No
Host: Mouse
Species reactivity: human (Expected: mouse, rat)
Immunogen: synthetic peptide corresponding to internal residues of human AKT3 protein
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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