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108 Antikörper Treffer
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mouse [4]
rat [1]
rabbit [2]
monkey [12]
dog [2]
cat [1]
 
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Human CD117 (c-​kit) is a transmembrane protein with receptor tyrosine kinase capacity and serves as the receptor for steel factor (SLF). CD117 is expressed on almost all hematopoietic progenitor cells and receptor/ligand interaction is crucial for develop ... mehr
Immunogen: Human MO7e tumor cells
57A5 Mouse
> sec. Ab
Mab IgG1
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​338-​050 120 tests

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Human CD46 is a cell surface glycoprotein expressed on almost all human cells except erythrocytes. CD46 is involved with regulation of complement activation and is also a measles virus receptor.
Immunogen: Human PBL and EBV transformed LCL
169-1-E4.3 Mouse
> sec. Ab
Mab IgG2a
human
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purified FC
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Ancell
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ANC-​197-​050 120 tests

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Human CD41 is a member of a major platelet transmembrane glycoprotein complex (CD41/CD61) which mediates platelet aggregation and adhesion by serving as the receptor for fibrinogen and von Willebrand factor, fibronectin and vitronectin.
Immunogen: Human PBL
96.2C1 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​190-​050 120 tests

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Human CD29 is the beta subunit of an integrin family of molecules expressed on diverse cell types which function as the major receptors for extracellular matrix and as cell-​cell adhesion molecules. CD29 can form heterodimer pairs with at least nine differ ... mehr
Immunogen: Human ocular melanoma cell line, V
4B7R Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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Ancell
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ANC-​178-​050 120 tests

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Human CD98 (4F2) is a heterodimeric glycoproein expressed on monocytes and activated cells. All cultured human cell lines tested express CD98. CD98 heavy chain mediates adhesion induced activation through integrin signaling.
Immunogen: Molt 13 T cell line
UM7F8 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​319-​050 120 tests

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Human CD44 molecules appear to serve as lymphocyte adhesion molecules with numerous functions in extracellular matrix binding, cell migration, hemopoisis and lymphocyte homing.
Immunogen: Human peripheral myeloma cells
BU52 Mouse
> sec. Ab
Mab IgG1
kappa
human
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ANC-​193-​050 120 tests

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Human CD44 molecules appear to serve as lymphocyte adhesion molecules with numerous functions in extracellular matrix binding, cell migration, hemopoisis and lymphocyte homing.
Immunogen: Human peripheral myeloma cells
BU75 Mouse
> sec. Ab
Mab IgG2a
human
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purified FC
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Ancell
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ANC-​352-​050 120 tests

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Human CD95 (APO-​1, Fas) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes. CD95 plays an important role in programmed cell death or apoptosis. Apoptosis appears to be a mechanism for ... mehr
Immunogen: Human soluble FAS with the transmembrane region deleted
ANC95.1 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
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Ancell
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ANC-​316-​050 120 tests

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Human CD26 is a T cell activation antigen which can be associated with costimulation. The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory ... mehr
Immunogen: Human T cell clone
202.36 Mouse
> sec. Ab
Mab IgG2b
human
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ANC-​175-​050 120 tests

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Human CD71 is a type II transmembrane glycoprotein found on activated leukocytes. CD71 binds transferrin and mediates uptake of iron through endocytosis and recycling.
Immunogen: Human PBL
DF1513 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
ICC
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Ancell
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ANC-​223-​050 120 tests

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Human CD54 (ICAM-​1) mediates cell adhesion by binding to the integrins CD11a/CD18 (LFA-​1) and to CD11b/CD18 (Mac-​1). CD54 expression on resting peripheral blood leukocytes is weak but is upregulated on activated T and B lymphocytes and on monocytes.
Immunogen: Human monocytes
15.2 Mouse
> sec. Ab
Mab IgG1
kappa
human
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Ancell
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ANC-​205-​050 120 tests

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Human CD54 (ICAM-​1) mediates cell adhesion by binding to the integrins CD11a/CD18 (LFA-​1) and to CD11b/CD18 (Mac-​1). CD54 expression on resting peripheral blood leukocytes is weak but is upregulated on activated T and B lymphocytes and on monocytes.
Immunogen: Human endothelial cells
8.4A6 Mouse
> sec. Ab
Mab IgG1
human, monkey
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Ancell
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ANC-​206-​050 120 tests

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Human CD104 (beta 4 integrin) associates with the alpha 6 integrin chain and binds to laminin and epiligrin and likely has cell-​cell adhesion functions. CD104 is involved in signal transduction.
Immunogen: UM-​SCC-​1, human squamous cell carcinoma
UMA9 Mouse
> sec. Ab
Mab IgG2a
human
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purified FC
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ANC-​325-​050 120 tests

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Human CD152 (CTLA-​4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-​1) and CD86 (B7-​2) and appears to function as a negative regulator of T cell acti ... mehr
Immunogen: Stimulated human PBL's and human CD152 Ig fusion protein
ANC152.2/8H5 Mouse
> sec. Ab
Mab IgG1
kappa
human, Pig, Cow, Cat, dog
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purified FC
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Ancell
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ANC-​359-​050 120 tests

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Human CD147 (EMMPRIN) is a transmembrane glycoprotein expressed more intensely on thymocytes than on mature peripheral blood T cells. Expression of CD147 in bronchial epithelial cells has been correlated with incidence of COPE.
Immunogen: Human T cell line Molt 13
UM-8D6 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
IP
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Ancell
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ANC-​376-​050 120 tests

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Human CD55 is a GPI anchored protein that can protect cells from complement mediated lysis.
Immunogen: Human monocytes
67 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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Ancell
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ANC-​207-​050 120 tests

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Human CD13 is a zinc-​binding aminopeptidase-​N enzyme expressed on the surface of myeloid cells. IL-​4 will upregulate expression of CD13 which may play an anti-​inflammatory role.
Immunogen: Human osteosarcoma tissue
22A5 Mouse
> sec. Ab
Mab IgG2a
kappa
human
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ANC-​162-​050 120 tests

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Human CD4 is a cell surface glycoprotein of 55kDa expressed on most thymocytes, on about two thirds of peripheral T cells and on some monocyte macrophage lineage cells. CD4 interacts with MHC Class II molecules in an accessory role during foreign antigen ... mehr
Immunogen: CD4 transfectant/human CEM
QS4120 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
ELISA
FA  ( Blocking ) Erklärungen der Abkürzungen ansehen.
Ancell
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ANC-​147-​050 120 tests

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Human CD4 is a cell surface glycoprotein of 55kDa expressed on most thymocytes, on about two thirds of peripheral T cells and on some monocyte macrophage lineage cells. CD4 interacts with MHC Class II molecules in an accessory role during foreign antigen ... mehr
Immunogen: P815 cells transfected with human CD4
M-T441 Mouse
> sec. Ab
Mab IgG2b
human, baboon
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purified FC
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Ancell
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ANC-​148-​050 120 tests

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Human CD18 (beta integrin) forms a heterodimer with either alphaL, alphaM, or alphaX integrins (CD11a, b or c). CD11/CD18 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses.
Immunogen: Human peripheral blood monocytes
IB4 Mouse
> sec. Ab
Mab IgG2a
human, monkey, rabbit
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ANC-​167-​050 120 tests

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Human CD31 is an adhesion molecule expressed on platelets, endothelial cells, leukocytes and their bone marrow precursors. CD31 plays a role in homophilic adhesion and heterophilic transendothelial migration.
Immunogen: Stimulated human leukocytes
158-2B3 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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ANC-​180-​050 120 tests

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Human CD51 is an integrin alpha v chain which can associate with five different integrin beta chains to form various adhesion molecules. The alpha v beta 3 integrin complex binds vitronectin at the RGD sequence and also can bind to fibrinogen, von Willebr ... mehr
Immunogen: Human ocular melanoma cell line (V)
P2W7 Mouse
> sec. Ab
Mab IgG1
kappa
human
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ANC-​202-​050 120 tests

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Human CD59 is a GPI anchored molecule that protects cells from complement-​mediated lysis. Studies are progressing to determine the regulatory mechanism for CD59 expression. A CD59-​like protein has been discovered on the causative agent of Amebic encephali ... mehr
Immunogen: Human K562 tumor cells
BRA-10G Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​211-​050 120 tests

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Human CD49f molecules are integrin alpha 6 chains that are expressed as heterodimers with CD29 (beta 1 integrin) or CD104 (beta 4 integrin) and function as adhesion receptors. CD49f is expressed on platelets, monocytes, T lymphocytes and thymoctyes.
Immunogen: UM-​UC-​9, human bladder cancer cells
BQ16 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
WB
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Ancell
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ANC-​356-​050 120 tests

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Human CD40 is a member of the TNF receptor family and is present on all B cells except plasma cells. CD40 is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 plays an important role in B cell activation and the interactio ... mehr
Immunogen: Murine L cells transfectants expressing human CD40
BE-1 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
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Ancell
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ANC-​189-​050 120 tests

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CD40 belongs to the TNF-​receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-​dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interac ... mehr
Immunogen: Murine L cells transfectants expressing human CD40
EA-5 Mouse
> sec. Ab
Mab IgG1
human, Rat
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purified FC
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Ancell
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ANC-​300-​050 120 tests

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Human CD105 (endoglin) is a homodimeric membrane glycoprotein virtually restricted to endothelial cells and present on some leukemia cells and minor subsets of bone marrow cells. CD105 binds to TGF-​beta1 and beta3 with high affinity.
Immunogen: Membrane preparation of human B-​lineage leukemia cells
SN6 Mouse
> sec. Ab
Mab IgG1
kappa
human
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ANC-​326-​050 120 tests

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Human CD74 is expressed intracellularly and on the cell surface of MHC Class II positive cells such as B cells, monocytes, macrophages, Langerhans cells and dendritic cells. CD74 has several important functions relating to antigen presentation by MHC Clas ... mehr
Immunogen: RPMI 1788 cell line
M-B741 Mouse
> sec. Ab
Mab IgG2a
human
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ANC-​226-​050 120 tests

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Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired i ... mehr
Immunogen: Human sgp39 fusion protein
24-31 Mouse
> sec. Ab
Mab IgG1
human, monkey
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ANC-​353-​050 120 tests

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Human CD63 is expressed on activated platelets and also on monocytes and macrophages. CD63 contains four hydrophobic transmembrane regions and is a member of the tetraspan family. CD63 appears to be involved with cell adhesion and associates with VLA-​3 an ... mehr
Immunogen: Human eosinophils
AHN16.1 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
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Ancell
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ANC-​215-​050 120 tests

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Human CD62P appears on the surface of activated endothelial cells or platelets and likely is involved with regulating the recruitment of leukocytes to areas of inflammation or infection.
Immunogen: Purified human platelet GMP-​140 (CD62P)
G1 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​252-​050 120 tests

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Human CD162 is the high affinity binding site for CD62P on leukocytes.
Immunogen: Purified (With Antibiotics) human neutrophil PSGL-​1
PL1 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
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Ancell
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ANC-​389-​050 120 tests

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Human CD10 is a well known marker for common acute lymphoblastic leukemia antigen (CALLA). CD10 is expressed on normal early B cells in bone marrow and is also on fetal thymocytes. CD10 expression is lost as the T and B lineage cells mature and only appea ... mehr
Immunogen: Membrane preparation of human B-​lineage leukemia cells
SN5c Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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Ancell
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ANC-​157-​050 120 tests

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Human CD64 is a high affinity receptor for monomeric human IgG1 and IgG3 which is expressed on macrophages, monocytes and gamma-​interferon induced neutrophils. CD64 plays an important role in clearance of immune complexes and in antibody dependent cytoxic ... mehr
Immunogen: Human rheumatoid synovial fluid cells/monocytes
10.1 Mouse
> sec. Ab
Mab IgG1
human, dog, monkey
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purified FC
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ANC-​216-​050 120 tests

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Human CD21 is a receptor for complement fragments C3d, C3dg or ic3D and also EBV. CD21 is also a ligand for CD23 and plays a role in IgE synthesis.
Immunogen: Human HFB-​1 cell line
BU33 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human, monkey
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purified FC
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Ancell
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ANC-​170-​050 120 tests

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Human CD84 is a cell surface glycoprotein found on mature B lymphocytes, monocytes and a subset of T lymphocytes.
Immunogen: Human MLR stimulated lymphocytes
152.1D5 Mouse
> sec. Ab
Mab IgG1
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​305-​050 120 tests

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Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-​specific alternative RNA splicing of exons 4-​7 of ... mehr
Immunogen: Cultured human T cell line-​CA-​1
UCHL1 Mouse
> sec. Ab
Mab IgG2a
human, monkey
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ANC-​194-​050 120 tests

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Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-​specific alternative RNA splicing of exons 4-​7 of a s ... mehr
Immunogen: Peripheral blood mononuclear cells
C11 Mouse
> sec. Ab
Mab IgG2a
kappa
human
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ANC-​196-​050 120 tests

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Human CD45RA is expressed on all cells of hematopoietic origin, except erythrocytes. CD45RA is a transmembrane tyrosine phosphate which can exist in at least nine different isoforms resulting from tissue-​specific alternative RNA splicing of exons 4-​7 of a ... mehr
Immunogen: Stimulated human leukocytes
158.4D3 Mouse
> sec. Ab
Mab IgG2a
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​394-​050 120 tests

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Human CD11b (alpha M integrin) complexes with CD18 (beta 2 integrin) to form the complement receptor type 3 (CR3) heterodimer which binds to ICAM-​1, fibrinogen, C3b and coagulation factor X. CD11b expression is restricted to leukocytes, mainly to myeloid ... mehr
Immunogen: Human monocytes
ICRF44 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human, monkey
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​159-​050 120 tests

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Human CD79a is a 22kDa glycoprotein which associates with CD79b to form a functional heterodimer that interacts with membrane immunoglobulin (mIg).The mIgM component binds antigen and the heterodimer transduces signals.
Immunogen: Daudi IgM complex
ZL7-4 Mouse
> sec. Ab
Mab IgG1
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​235-​050 120 tests

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Human CD62E (E-​selectin) is an adhesion molecule expressed on activated endothelium and facilitates recruitment of leukocytes to sights of acute inflammation and immunological events. CD62E has affinity to Lewis x.
Immunogen: TNF activated HUVEC
HAE-1f Mouse
> sec. Ab
Mab IgG1
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​240-​050 120 tests

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Human CD9 is strongly expressed on platelets, on early B cells and on activated T cells. CD9 is a member of the tetraspan family crossing the membrane four times. Both the N-​terminal and C-​terminal regions are on the cytoplasmic side of the plasma membran ... mehr
Immunogen: Membrane antigen preparation of NALM-​6
SN4 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​156-​050 120 tests

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Human CD49b is an integrin alpha2 subunit that forms a heterodimer with beta1 integrin and functions as an adhesion molecule.
Immunogen: Human cultured keratinocytes
HAS6 Mouse
> sec. Ab
Mab IgG2a
kappa
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​155-​050 120 tests

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Human CD106 is an endothelial adhesion molecule that binds to alpha 4 beta 1 and alpha 4 beta 7 integrins (VLA-​4) and promotes adhesion of lymphocytes, monocytes, eosinophils and basophils. CD106 is also found on follicular dendritic cells, interdigitatin ... mehr
Immunogen: Human endothelial cells
1.G11B1 Mouse
> sec. Ab
Mab IgG1
human, Pig
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purified FC
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ELISA
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Ancell
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ANC-​327-​050 120 tests

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Human CD62L is as adhesion molecule found on most leukocytes and plays a primary role in mediating initial leukocyte interaction with activated vascular endothelium. Human CD62L has signal transduction functions where engagement leads to increased calcium ... mehr
Immunogen: Mouse pre-​B cells expressing human L-​selectin
LAM1-116 Mouse
> sec. Ab
Mab IgG2a
kappa
human, horse, mouse
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​261-​050 120 tests

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Human CD32 exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-​transducing capabilities involved with humoral and cell-​medi ... mehr
Immunogen: Human K562 tumor cells and L cells transfected with human Fc gamma RII
7.3 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​181-​050 120 tests

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Human CD81 is a member of the tetraspan family of leukocyte cell surface molecules which are involved in signal transduction, cell-​cell adhesion and cellular activation. Association of CD81 with integrins appears to be functionally important in the regula ... mehr
Immunogen: Human B cell line from Burkitt lymphoma
1.3.3.22 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
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ANC-​302-​050 120 tests

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Human CD270 (Herpes Virus Entry Mediator, TNFRSF14, ATAR, LIGHTR, TR2) is a 36kDa type I membrane protein that has been found on a broad range of lymphoid tissues. Its ligands include the TNF ligand family members LTalpha and LIGHT and the CD28/Ig superfa ... mehr
Immunogen: Recombinant  human CD270(HVEM)
ANC3B7 Mouse
> sec. Ab
Mab IgG2a
kappa
human
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purified FC
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Ancell
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ANC-​270-​050 120 tests

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The human CD1 genetic locus consists of five closely related genes. Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional an ... mehr
Immunogen: Human Jurkat tumor cells
CB-T6 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​145-​050 120 tests

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Human CD2 is a T-​lineage glycoprotein with roles in cell-​cell adhesion and the transduction of activation signals. Multiple ligands for CD2 include CD58 (LFA-​3), CD59, and CD48. CD2 may play a role in regulating T cell anergy.
Immunogen: Human rheumatoid synovial T cell line (ST-​1)
1E7E8 Mouse
> sec. Ab
Mab IgG2a
kappa
human
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purified FC
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ANC-​143-​050 120 tests

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Human CD14 is strongly expressed on myelomonocyte lineage cells including monocytes, macrophages and a subset of granulocytes. CD14 is a high affinity receptor for complexes of lipopolysaccharide and lipopolysaccharide binding protein. A soluble form of C ... mehr
Immunogen: Human thymocytes/Sezary T cells
UCHM1 Mouse
> sec. Ab
Mab IgG2a
human
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ANC-​163-​050 120 tests

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Human CD28 is an important costimulatory molecule found on all CD4 T cells and on about half of the CD8 T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA an ... mehr
Immunogen: Recombinant Human CD28 and HPB-​MLT human tumor cells
ANC28.1/5D10 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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ANC-​177-​050 120 tests

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Human CD19 is a B cell restricted membrane protein expressed from early stages of B cell development and associates with the antigen receptor complex. CD19 is involved in the regulation of B cell proliferation.
Immunogen: Human EB-​4 Burkitt lymphoma cell line
BU12 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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ANC-​168-​050 120 tests

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Human CD79b is the B cell antigen receptor Ig beta chain (BCR-​Ig beta) which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg) (3). The mIgM component binds antigen a ... mehr
Immunogen: Membrane preparation of human B prolymphocytic leukemia cells
SN8 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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ANC-​301-​050 120 tests

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Human CD86 (B7-​2) is a costimulating ligand for CD28 and CTLA-​4. CD86 is expressed on activated B cells and blood monocytes.
Immunogen: ARH-​77 (B-​lymphoblastoid cell line)
BU63 Mouse
> sec. Ab
Mab IgG1
human, monkey
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ANC-​307-​050 120 tests

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Human CD23 is a low affinity receptor for IgE (Fc epsilon RII) found primarily on mature B cells and also on eosinophils, monocytes, dendritic cells, platelets and a subset of thymic epithelial cells. CD23 interacts with CD21.
Immunogen: Human peripheral myeloma cells
BU38 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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ANC-​172-​050 120 tests

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Human CD49d molecules are integrin alpha4 chains that are expressed as heterodimers with CD29 (beta 1 integrin) or (beta 7 integrin) and function as adhesion receptors. CD49d/CD29 is mainly expressed on thymocytes and B cells with increased expression on ... mehr
Immunogen: Human peripheral myeloma cells
BU49 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​200-​050 120 tests

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Human CD11a (alpha L integrin) complexes with CD18 (beta 2 integrin) to form the LFA-​1 heterodimer adhesion molecule which binds to three ICAM's 1, 2, and 3, also designated CD54, CD102 and CD50 respectively. LFA-​1 is expressed on lymphocytes, monocytes ... mehr
Immunogen: Human monocytes
38 Mouse
> sec. Ab
Mab IgG2a
human
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ANC-​158-​050 120 tests

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Human CD30 is a member of the TNF receptor family and is expressed on mitogen activated B and T cells.
Immunogen: Human YT lymphoma cells
AC10 Mouse
> sec. Ab
Mab IgG2b
kappa
human
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ANC-​179-​050 120 tests

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Human CD50 (ICAM-​3) is an adhesion molecule that interacts with LFA-​1 (CD18/CD11a) and provides a costimulatory signal for T cells which is thought to be essential for initiation of immune responses.
Immunogen: Stimulated human leukocytes
186-2G9 Mouse
> sec. Ab
Mab IgG2b
human
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ANC-​201-​050 120 tests

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Human Fas ligand (CD95L, CD178) is a 40kDa type II membrane protein that induces apoptosis in cells expressing Fas (CD95). Fas ligand is one of the major effectors of CD8? and NK activity. Loss of Fas ligand leads to lymphoproliferative and autoimmune dis ... mehr
Immunogen: Soluble human FAS Ligand
ALF-2.1A Mouse
> sec. Ab
Mab IgG1
human
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ANC-​399-​050 120 tests

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Human CD166 is a type 1 glycoprotein expressed on activated T cells, B cells and monocytes and appears to be the ligand for CD6. Human CD166 may be important for activation of T cells.
Immunogen: Human thymic epithelial cells
3A6 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​393-​050 120 tests

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Expression of human CD25 (the alpha subunit of the IL-​2 receptor complex) is dramatically upregulated on activated T cells, B cells, NK cells and macrophages. Antibodies to CD25 are being studied for potential use as an immunodirected therapy to selective ... mehr
Immunogen: Stimulated PBMC
7G7B6 Mouse
> sec. Ab
Mab IgG2a
human
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purified FC
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ANC-​174-​050 120 tests

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Human CD8 is a heterodimeric protein consisting of an alpha and beta chain, each about 33kDa. CD8 is expressed on most thymocytes and on about one third of peripheral blood T cells. CD8 is a co-​receptor involved in antigen recognition and binds to the alp ... mehr
Immunogen: Human thymocytes/Sezary T cells
UCHT4 Mouse
> sec. Ab
Mab IgG2a
human
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purified FC
ELISA
WB
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Ancell
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ANC-​153-​050 120 tests

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Human CD8 is a heterodimeric protein consisting of an alpha and beta chain, each about 33kDa. CD8 is expressed on most thymocytes and on about one third of peripheral blood T cells. CD8 is a co-​receptor involved in antigen recognition and binds to the alp ... mehr
Immunogen: Human thymocytes
14 Mouse
> sec. Ab
Mab IgG1
kappa
human
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ANC-​154-​050 120 tests

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The human CD3/T cell receptor (TcR) complex is made up of the CD3 proteins (gamma, delta, 2 epsilon) and teh zeta-​chain in association with either alpha/beta or gamma/delta proteins of the TcR. The TcR recognizes antigens in association with MHC molecules ... mehr
Immunogen: Human thymocytes/Sezary T cells
UCHT1 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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purified FC
WB
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ANC-​144-​050 120 tests

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The human CD1 genetic locus consists of five closely related genes. Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional an ... mehr
Immunogen: Membrane antigen preparation of human thymocytes
SN13 Mouse
> sec. Ab
Mab IgG1
kappa
human
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ANC-​142-​050 120 tests

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Human CD39 is found on most mature B cells, activated NK cells and activated T cells, as well as neutrophills and monocytes. CD39 has homology to the N-​myc family of proteins and has been cloned. CD39 is an ecto apyrase. A lower expression level of CD39 o ... mehr
Immunogen: Human WM-​1 (Waldenström's macroglobulinemia) cell line
BU61 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​188-​050 120 tests

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Human CD5 is believed to be an alternative signaling molecule found on all mature T cells, on most thymocytes and on a subpopulation of mature B cells expressing autoantibodies. The ligand for CD5 is CD72.
Immunogen: Human thymocytes/Sezary T cells
UCHT2 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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ANC-​150-​050 120 tests

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Human CD20 has four membrane-​spanning domains and forms a homo-​oligomeric calcium ion channel complex critical for normal B cell function. CD20 is a B cell restricted antigen.
Immunogen: Human Ia¯  B cell line 616c13
2H7 Mouse
> sec. Ab
Mab IgG2b
human, monkey
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ANC-​169-​050 120 tests

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Human CD43 is a heavily O-​glycosylated and sialylated transmembrane protein that is mainly found on T cells, but not on B cells.
Immunogen: Human KG-​1 tumor cells
DFT1 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​192-​050 120 tests

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Human CD35 binds complement components C3b, C4b and iC3b and is expressed on erythrocytes, B cells, monocytes, granulocytes and folicular dendritic cells and on subsets of thymocytes. CD35 on erythrocytes mediates clearance of immune complexes.
Immunogen: Human monocytes
E11 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
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ANC-​184-​050 120 tests

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Human CD58 is a cell surface glycoprotein with wide distribution on hemopoietic cells and functions as an adhesion molecule mediating a costimulatory signal through CD2. CD58 is attached to the cell surface by either of two forms -​ transmembrane or GPI.
Immunogen: Human cytotoxic  T cells
TS2 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​210-​050 120 tests

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Human CD27 is a lymphocyte specific member of the TNF receptor family and is found primarily on peripheral blood T cells and on a subpopulation of B cells and NK cells. The ligand for CD27 is CD70, which is a member of the TNF ligand superfamily.
Immunogen: T cell line (from patient with CLL)
M-T271 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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purified FC
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ANC-​176-​050 120 tests

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Human CD38 is a type II transmembrane glycoprotein with bifunctional ectoenzyme activity catalyzing both synthesis and hydrolysis of cyclic ADP ribose. CD38 is involved in lymphocyte activation and adhesion to endothelium and has been identified as a cou ... mehr
Immunogen: Human T cell tumor cells: CEM
AT1 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​187-​050 120 tests

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The human CD1 genetic locus consists of five closely related genes. Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional an ... mehr
Immunogen: Human T cell line Molt 4
M241 Mouse
> sec. Ab
Mab IgG1
kappa
human, rabbit
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purified FC
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ANC-​146-​050 120 tests

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Human CD137 (4-​1BB) is expressed on activated T cells within 24-​48 hours of activation. CD137 is a type I membrane protein and a member of the TNF receptor superfamily. CD137 appears to be important for T cell proliferation and survival and induces monocy ... mehr
Immunogen: Ectodomain of recombinant human 4-​1BB fusion protein
4B4-1 Mouse
> sec. Ab
Mab IgG1
kappa
human, monkey
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purified FC
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ANC-​360-​050 120 tests

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Human CD48 is a GPI anchored cell surface gylcoprotein found on all lymphocytes and monocytes. CD48 is a ligand for CD2 and may be involved in enhancing the activating signal to B cells.
Immunogen: Human PBLs
5-4.8 Mouse
> sec. Ab
Mab IgG2a
human
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ANC-​199-​050 120 tests

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Human CD33 is a 67kDa sialoadhesin belonging to the Ig superfamily. It is expressed on normal myeloid cells an precursors, as well as myeloid leukemias, but is not present on stem cells.
Immunogen: Human Acute Myeloblastic Leukemia cells
WM-53 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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ANC-​182-​050 120 tests

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Human CD22 expression is restricted to normal Ig mature B cells and neoplastic B cells. CD22 is a transmembrane glycoprotein of 140kDa with a predicted adhesion molecule function.
Immunogen: Human tonsil lymphocytes
RFB4 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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ANC-​171-​050 120 tests

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Human CD80 (B7-​1) is a costimulatory ligand for CD28 and CD152 (CTLA-​4). CD80 is expressed on activated B cells.
Immunogen: Human CD80 (B7-​1) Ig Fusion Protein
P1.H1.A1.A1 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
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ANC-​110-​050 120 tests

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Human CD7 is one of the earliest T lineage markers and is found on most thymocytes and peripheral blood T cells. The function of CD7 is not yet fully known, although cross-​linking of CD7 with antibodies induces a T cell transmembrane calcium flux and CD ... mehr
Immunogen: Human HSB2-​T cells
3A1E Mouse
> sec. Ab
Mab IgG2b
human
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ANC-​152-​050 120 tests

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Human CD56 is an adhesion molecule from the Ig superfamily which is restricted to NK cells and a subset of T cells in the immune system. It is believed that NK cells form a first line of defense against tumor cells and cells infected with bacteria and vir ... mehr
Immunogen: Recombinant human CD56 (truncated domains 1-​4 only)
ANC7C7 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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ANC-​308-​050 120 tests

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CD127 (IL-​7Ra) is the specific receptor component for the cytokine interleukin-​7 (IL-​7). It is found on a wide variety of hematopoietic cell types including B cell precursors and the majority of T cells. Its expression levels are decreased on T cells foll ... mehr
Immunogen: Recombinant human CD127
ANC8F2 Mouse
> sec. Ab
Mab IgG1
kappa
human
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ANC-​348-​050 120 tests

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Human CD34 is an unusual glycosylated membrane protein exclusively expressed on immature hematopoietic cells and on endothelial cells. CD34 may have a role in cell adhesion. CD34 has extensive utility for bone marrow transplantation.
Immunogen: Human KG-​1a tumor cells
43A1 Mouse
> sec. Ab
Mab IgG3
kappa
human, monkey
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purified FC
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ANC-​183-​050 120 tests

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Human CD94 expression is restricted to natural killer (NK) cells and a small subset of T lymphocytes. CD94 is a type II membrane glycoprotein of the C-​type lectin superfamily and essentially lacks a cytoplasmic tail.
Immunogen: Cultured human NK cells
HP-3D9 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​315-​050 120 tests

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Human CD268 (BAFFR, BAFF receptor) is a type I TNF superfamily receptor member #13c. It is highly specific for CD257 (BAFF)., which itself does bind to other receptors TACI, and BCMA. CD268 expressed on B cells and its ligation by CD257 (BAFF) regul ... mehr
Immunogen: Recombinant human CD268
ANC268.2/6E6 Mouse
> sec. Ab
Mab IgG2
kappa
human
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purified ELISA
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ANC-​275-​050 120 tests

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Human CD11c (alpha X integrin) complexes with CD18 (beta 2 integrin) to form the complement receptor type 4 (CR4) heterodimer which binds to fibrinogen and is involved with monocyte/granulocyte adhesion during inflammatory responses. CD11c expression is r ... mehr
Immunogen: Human rheumatoid synovial fluid cells/monocytes
3.9 Mouse
> sec. Ab
Mab IgG1
Mouse IgG1
human
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ANC-​160-​050 120 tests

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Human CD134 (OX40, ACT35) is an activation-​associated antigen which is predominantly expressed on activated CD4 positive cells. CD134 antigen is a member of the TNF receptor family of molecules and may be involved with regulating T cell-​dependent B cell p ... mehr
Immunogen: Human HUT 102 T cells
BerAct35 Mouse
> sec. Ab
Mab IgG1
human
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purified FC
ELISA
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ANC-​355-​050 120 tests

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Human CD161 is a homodimeric disulfide-​linked type II membrane bound glycoprotein found mainly on NK cells. CD161 has been implicated in the regulation of NK cell mediated cytotoxicity.
Immunogen: Activated human NK cells
B199.2 Mouse
> sec. Ab
Mab IgG2b
human
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ANC-​388-​050 120 tests

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Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-​1 and CTLA-​4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand ... mehr
Immunogen: Recombinant extracellular human CD272
ANC6E9 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
ELISAErklärungen der Abkürzungen ansehen.
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ANC-​272-​050 120 tests

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Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-​1 and CTLA-​4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand ... mehr
Immunogen: Recombinant extracellular human CD272
ANC5A5 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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ANC-​372-​050 120 tests

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Glucocorticoid induced TNF receptor family related gene (GITR, AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4 CD25 T lymphocytes. Its engagement by antibodies or its ligand (GITRL) ... mehr
Immunogen: Recombinant human GITR, PHA stimulated human PBL
ANC5E3 Mouse
> sec. Ab
Mab IgG3
kappa
human
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purified FC
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ANC-​368-​050 120 tests

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The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Secondary signaling through CD28 or CD278 results in discrete cytokine secretion profiles by the activated T cell ... mehr
Immunogen: Human HPB-​MLT cells, recombinant human CD278(ICOS)-​muIg
ANC6C6 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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ANC-​265-​050 120 tests

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CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.
Immunogen: Mouse CTL-​V4 membrane prep
GK1.5 Rat
> sec. Ab
Mab IgG2b
kappa
mouse
Erklärungen der Abkürzungen ansehen.
purified FC
ELISA
IHC
IPErklärungen der Abkürzungen ansehen.
Ancell
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ANC-​704-​050 120 tests

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Human CD37 is a member of the tetraspan family of cell surface molecules that apparantly are involved in signal transduction or transporter system complexes. CD37 is strongly expressed on B lymphocytes (sIg-​positive) and weakly on T cells, neutrophils and ... mehr
Immunogen: Human spleen cells from a patient with hairy cell leukemia
IPO-24 Mouse
> sec. Ab
Mab IgG2b
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​186-​050 120 tests

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Human CD53 is a tetraspan cell surface glycoprotein found on all hemopoetic cells except platelets and red blood cells.
Immunogen: Human sezary cells
63.5A3 Mouse
> sec. Ab
Mab IgG2b
human
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ANC-​204-​050 120 tests

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Human CD252 (CD134L, OX40 ligand) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD252 binds to CD134 (OX40) present on activated T cells, providing a costimulatory signal. Bloc ... mehr
Immunogen: Human HUVEC and Recombinant soluble human CD134L
ANC10G1 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
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Ancell
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ANC-​400-​050 120 tests

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Human CD83 is a type 1 cell surface glycoprotein expressed almost solely by dendritic cells that play an important role in antigen presentation.
Immunogen: COS cells transfected with human CD83
HB15e Mouse
> sec. Ab
Mab IgG1
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​304-​050 120 tests

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Human CD69 is expressed by platelets and mature thymocytes and appears rapidly after activation on T cells, B cells and NK cells. This pattern of cellular CD69 expression has suggested a lymphocyte activation role. Functional studies with antibodies to CD ... mehr
Immunogen: IL-​2 activated human NK cells
HP-4B3 Mouse
> sec. Ab
Mab IgG2a
human
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purified FCErklärungen der Abkürzungen ansehen. Ancell
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ANC-​221-​050 120 tests

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CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-​alpha chains binds to Class I MHC molecules alpha-​3 domains. Defects in CD8A are a cau ... mehr
Immunogen: murine thymocytes/splenocytes
53-6 Rat
> sec. Ab
Mab IgG2a
kappa
mouse
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purified FC
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Ancell
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ANC-​260-​050 120 tests

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Human CD70 is not present on resting lymphocytes. CD70 is expressed after activation on about 20% of T cells and on about 70% of B cells. CD70 is a ligand for CD27 and it is also a member of the TNF gene family.
Immunogen: Human WM-​1 (Waldenström's macroglobulinemia) cell line
BU69 Mouse
> sec. Ab
Mab IgG1
human, monkey
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purified FC
ELISA
ICC
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Ancell
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ANC-​222-​050 120 tests

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Human CD6 is expressed on peripheral blood T cells, most thymocytes and a subset of B cells. CD6 is similar to CD5 and contains three cysteine-​rich domains with structural homology to the macrophage scavenger receptor. CD6 is involved in T cell activation ... mehr
Immunogen: Human rheumatoid synovial T cell line (ST-​1)
3F7B6 Mouse
> sec. Ab
Mab IgG1
kappa
human
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purified FC
WBErklärungen der Abkürzungen ansehen.
Ancell
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ANC-​151-​050 120 tests

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CD3 molecules associate with T cell receptors and provide intracellular signaling mechanism.
Immunogen: Mouse BM10-​37 T cell membrane prep
145-2C11 Hamster
> sec. Ab
Mab IgG
mouse
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purified FC
IP
WB
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Ancell
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ANC-​703-​050 120 tests

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Human CD137 ligand is a type II transmembrane protein constitutively expressed by monocytes, B cells neuroblastoma cells, and some activated T cells. The interaction of CD137 (4-​1BB) and CD137L can supply a costimulatory signal to T cells through CD137. T ... mehr
Immunogen: Recombinant human CD137L
ANC5D6 Mouse
> sec. Ab
Mab IgG2a
kappa
human
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purified FC
ELISA
WBErklärungen der Abkürzungen ansehen.
Ancell
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ANC-​365-​050 120 tests

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Human CD16 is a low affinity receptor for complexed IgG and occurs in two distinct forms, as a glycosyl phosphatidyl inositol (GPI) anchored protein in granulocytes and as an integral membrane protein on NK cells and macrophages.
Immunogen: Human polymorphonuclear leukocytes
3G8 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​165-​050 120 tests

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Human CD165 is a cell surface molecule present on a subset of peripheral lymphocytes and monocytes and is important for adhesion of thymocytes to thymic epithelial cells.
Immunogen: HSB cells
AD2 Mouse
> sec. Ab
Mab IgG1
human
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ANC-​392-​050 120 tests

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