19 products were found matching "2877-1"!

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Anti-SOX13
Anti-SOX13

Item number: E-AB-12877.120

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been...
Keywords: Anti-SOX13, Anti-Islet cell antigen 12, Anti-Transcription factor SOX-13, Anti-Type 1 diabetes autoantigen ICA12, Anti-SRY...
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human, mouse
From 71.00€ *
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Anti-HMBOX1
Anti-HMBOX1

Item number: E-AB-52877.120

Transcription factor.Ubiquitous. Detected in pancreas, brain, spleen, placenta, prostate, thymus, liver, heart, bone marrow, skeletal muscle, stomach, uterus, testis, kidney, ovary, and colon. Protein function: Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA (PubMed:23813958, PubMed:23685356). Associates...
Keywords: Anti-Homeobox-containing protein 1, Anti-Homeobox telomere-binding protein 1, Anti-Telomere-associated homeobox-containing...
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human, mouse
From 71.00€ *
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Anti-KDM4C
Anti-KDM4C

Item number: E-AB-92877.120

This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in...
Keywords: KDM4C, GASC1, GASC-1 protein, Lysine-specific demethylase 4C, Jumonji domain-containing protein 2C, [histone...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
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Anti-CD73 (Immuno-Oncology Target) Monoclonal Antibody (Clone: NT5E/2505)
Anti-CD73 (Immuno-Oncology Target) Monoclonal Antibody...

Item number: ABE-36-2877-100

CD73 (also designated ecto-5'-nucleotidase, E5NT, NT, NT5, NTE, eN and eNT) is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical...
Keywords: Anti-NT5, Anti-NT5E, Anti-CD73, Anti-5'-NT, EC=3.1.3.5, Anti-5'-nucleotidase, Anti-Ecto-5'-nucleotidase, Anti-CD73...
Application: WB, FC, IF, IHC
Host: Mouse
Species reactivity: human
From 375.00€ *
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Hoxa4, Mouse homeo box A4, Real Time PCR Primer Set
Hoxa4, Mouse homeo box A4, Real Time PCR Primer Set

Item number: VMPS-2877

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: Hoxa4, Homeobox protein MH-3, Homeobox protein Hox-A4, Homeobox protein Hox-1.4
Application: RNA quantification
43.00€ *
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Dacarbazine
Dacarbazine

Item number: Cay21877-500

Dacarbazine is a DNA alkylating prodrug that is activated by P450 enzymes in liver microsomes. Following activation, it is converted, through a series of reactions, into a methyldiazonium cation that alkylates DNA at all phases of the cell cycle and induces apoptosis. In vitro, dacarbazine inhibits the growth of...
Keywords: NCI C04717, NSC 45388, 5-(3,3-dimethyl-1-triazen-1-yl)-1H-imidazole-4-carboxamide
Application: DNA alkylating prodrug
CAS 4342-03-4
MW: 182.2 D
From 73.00€ *
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Ro 08-2750
Ro 08-2750

Item number: Cay28772-1

Ro 08-2750 is a p75 neurotrophin receptor (p75NTR) ligand that completely inhibits nerve growth factor (NGF) binding to p75NTR in PC12 cells when used at a concentration of 100 µM. It also binds to NGF dimers (Kd = ~1 µM) to induce a conformational change that prevents NGF binding to p75NTR or tropomyosin-related...
Keywords: 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo-benzo[g]pteridine-8-carboxaldehyde
Application: p75 neurotrophin receptor (p75NTR) ligand
CAS 37854-59-4
MW: 270.2 D
From 50.00€ *
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Nitisinone-13C6
Nitisinone-13C6

Item number: Cay28770-1

Nitisinone-13C6 is intended for use as an internal standard for the quantification of nitisinone (Cay-17924) by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway. Nitisinone...
Keywords: NTBC-13C6, 2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione-1,2,3,4,5,6-13C6
Application: GC-MS, LC-MS, Internal standard, 4-hydroxyphenylpyruvate dioxygenase inhibitor
CAS 1246815-63-3
MW: 335.2 D
530.00€ *
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CTEP
CTEP

Item number: Cay28773-10

CTEP is an inverse agonist of metabotropic glutamate receptor 5 (mGluR5, Kis = 16.4, 12.6, and 9.5 nM for the human, rat, and mouse receptors, respectively, in a radioligand binding assay). It is selective for mGluR5 over mGluR1, -2, -3, -4, -6, -7, and -8 (IC50s = >10 µM for all) and the histamine H1 and...
Keywords: 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]-1H-imidazol-4-yl]ethynyl]-pyridine
Application: mGluR5 inverse agonist
CAS 871362-31-1
MW: 391.8 D
From 163.00€ *
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PF-04995274
PF-04995274

Item number: Cay28776-1

PF-04995274 is a partial agonist of the serotonin (5-HT) receptor subtypes 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E (Kis = 0.36, 0.46, 0.15, and 0.32 nM, respectively, in a radioligand binding assay). It increases cAMP levels in HEK293 cells expressing 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E receptors (EC50s = 0.47, 0.36,...
Keywords: tetrahydro-4-[[4-[[[4-[[(3R)-tetrahydro-3-furanyl]oxy]-1,2-benzisoxazol-3-yl]oxy]methyl]-1-piperidinyl]methyl]-2H-pyran-4-ol
Application: 5-HT4A / 5-HT4B / 5-HT4D / 5-HT4E partial agonist
CAS 1331782-27-4
MW: 432.5 D
From 46.00€ *
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AMN082
AMN082

Item number: Cay28779-10

AMN082 is an orally bioavailable allosteric agonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits cAMP accumulation induced by forskolin in CHO cells expressing human mGluR7b (EC50 = 64 nM). AMN082 (10 µM) is selective for mGluR7a and mGluR7b over mGluR1b, mGluR4, and mGluR8a with 140, 90, 15, 18, and...
Keywords: N,N'-bis(diphenylmethyl)-1,2-ethanediamine, dihydrochloride
Application: Allosteric mGluR7 antagonist
CAS 97075-46-2
MW: 465.5 D
From 97.00€ *
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1,2,3-Trinonanoyl Glycerol
1,2,3-Trinonanoyl Glycerol

Item number: Cay28177-100

1,2,3-Trinonanoyl glycerol is a triacylglycerol that contains nonanoic acid at the sn-1, sn-2, and sn-3 positions. It has been found in Schizochytrium biomass. 1,2,3-Trinonanoyl glycerol increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in newborn rhesus monkeys.Formal Name: nonanoic acid,...
Keywords: Glyceryl Trinonanoate, NSC 5647, Trinonanoin, Tripelargonin, nonanoic acid, 1,1',1"-(1,2,3-propanetriyl) ester
Application: Triacylglycerol
CAS 126-53-4
MW: 512.8 D
From 43.00€ *
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