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NAME RUBRIK SPEZIES FORMAT MESST. FUNKTIONSW. PROBENTYP ANWENDUNG HERST. KAT # MENGE PREIS











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Progranulin (human) ELISA Kit (5 x 96 wells)
Ligands , Mediators human
Erklärungen der Abkürzungen ansehen.
solid phase Photometr. Immunological Lysates, Fluids ELISAErklärungen der Abkürzungen ansehen. Adipogen
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AG-​45A-​0018PP-​KI01 480 wells

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Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Culture Supernatant , Plasma , Serum. Sensitivity: 32pg/ml. Range: 0.063 to 4ng/ml. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-​edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer's Disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

Datenblatt ansehen
Manual
Kat #:
AG-45A-0018PP-KI01
Menge:
480 wells

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Preis:
1.914 €

UniProt ID: P28799 (Protein knowledgebase)

Schlagworte:
Proepithelin, PEPI, PC Cell-​derived Growth Factor
Image Art AG-45A-0018 Adipogen Progranulin (human) ELISA Kit  (5 x 96 wells)
Figure legend: Datenblatt ansehen

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