Limit of detection: 32 pg/ml. Progranulin (PGRN) is an autocrine growth factor that plays a role in embryonic development, tissue repair, tumorigenesis, and inflammation. Recently, PGRN has been shown to bind directly to tumor necrosis factor receptors (TNFR) where it antagonizes TNF-alpha signaling, effectively blocking the pathogenesis of inflammatory arthritis in mice. Furthermore, elevated serum concentrations of PGRN are associated with visceral obesity, elevated plasma glucose, and dyslipidemia. In the central nervous system, PGRN is thought to be involved in neurotrophic activity and neuroinflammation. Cayman's Progranulin (human) EIA Kit is an immunometric assay which can be used to measure progranulin in human serum, plasma, or cell culture supernatants. The assay exhibits a detection limit of 32 pg/ml and an assay range of 0-4 ng/ml.
Datenblatt ansehen
Manual
Kat #: Cay500940-1
Menge: 96 wellsBuy Bulk
Preis: 599 €
UniProt ID: P28799 (Protein knowledgebase)
Schlagworte:
GRN, PEPI, Granulins, Granulin-1, Granulin E, Granulin-6, Granulin D, Acrogranin, Granulin G, Granulin-3, Granulin-2, Granulin B, Granulin-4, Granulin-7, Granulin A, Granulin-5, Granulin F, Granulin C, Proepithelin, Paragranulin
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| Weitere Produkte für dieses Protein:Antibodies
- Anti-Granulin (GRN), Kat #: IMG-30843
- Anti-Granulin (GRN, GEP, GP88, PCDGF, PEPI, PGRN, PC cell-derived growth factor, acrogranin, granulin-epithelin, proepithelin, progranulin), Kat #: G8944-50E.100
- Anti-Granulin (GRN, GEP, GP88, PCDGF, PEPI, PGRN, PC cell-derived growth factor, acrogranin, granulin-epithelin, proepithelin, progranulin), Kat #: G8944-50C.100
- Anti-Granulin (GRN, GEP, GP88, PCDGF, PEPI, PGRN, PC cell-derived growth factor, acrogranin, granulin-epithelin, proepithelin, progranulin), Kat #: G8944-50B.100
- Anti-Granulin (GRN, Progranulin, PGRN, GEP, GP88, PC Cell Derived Growth Factor, PCDGF, Proepithelin, PEPI) (Azide Free), Kat #: G8944-50D.100
- Anti-Granulin / GRN, Kat #: WA-AF1504a
- Anti-Granulin C (human), Kat #: AG-25A-0090-C100
- Anti-Granulin/GRN, Kat #: IMG-30869
- Anti-GRN (monoclonal) (M01), Kat #: WA-AT2266a
- Anti-Progranulin (human), Kat #: AG-25A-0112-C100
- more
siRNA
Plasmids/Vectors
ELISA and Assay Kits
Primers
Cytokines
- Granulin C (human, rec.) (His), Kat #: AG-40A-0129-C010
- Granulin C (human, rec.) (His), Kat #: AG-40A-0129-C050
- Progranulin (human) (rec.) (untagged), Kat #: AG-40A-0188-C050
- Progranulin (human) (rec.) (untagged), Kat #: AG-40A-0188-C010
- Progranulin (human) (rec.) (untagged) (BULK), Kat #: AG-40A-0188AA-C500
- Progranulin (human, rec.), Kat #: AG-40A-0068-C010
- Progranulin (human, rec.), Kat #: AG-40A-0068-C050
- Progranulin, FLAG Tag, human recombinant (rHuPGRN-FLAG-HEK), Kat #: 97208.2
- Progranulin, FLAG Tag, human recombinant (rHuPGRN-FLAG-HEK), Kat #: 97208.1
- Progranulin, FLAG Tag, human recombinant (rHuPGRN-FLAG-HEK), Kat #: 97208.10
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