Nitrotyrosine is a post-translational modification that is formed by the nitration of tyrosine. It exists in a free or protein-bound form and is commonly used as a marker of nitrosative or oxidative stress. Nitrotyrosine residues have been found in a variety of proteins, including LDL, surfactant protein A,...

Dienestrol is a synthetic non-steroidal estrogen receptor (ER) agonist and an active metabolite of diethylstilbestrol (Cay-10006876). Dienestrol binds to ERalpha and ERbeta (Kis = 0.05 and 0.03 nM, respectively) and activates ERalpha in a reporter assay (EC50 = 3.23 nM). It also inhibits porcine microtubule assembly...