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Item number: A301-981A-T

Protein function: Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity. [The UniProt Consortium]

Keywords:	Anti-PACSIN3, Anti-SH3 domain-containing protein 6511, Anti-Protein kinase C and casein kinase substrate in neurons protein 3
Application:	WB, IP
Host:	Rabbit
Species reactivity:	human

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Anti-APC

Item number: A300-981A

Protein function: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration....

Keywords:	Anti-APC, Anti-DP2.5, Anti-Protein APC, Anti-Deleted in polyposis 2.5, Anti-Adenomatous polyposis coli protein
Application:	WB, IP, IHC
Host:	Rabbit
Species reactivity:	human

From 164.00€ *

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