Anti-trimethyl-phospho-Histone H3 (Trimethyl Lys27, pSer28)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-I84 50 µg - -

6 - 10 business days*

713.00€
 
Anti-Histone H3 [Trimethyl Lys27, p Ser28] was affinity purified from monospecific antiserum by... more
Product information "Anti-trimethyl-phospho-Histone H3 (Trimethyl Lys27, pSer28)"
Anti-Histone H3 [Trimethyl Lys27, p Ser28] was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined. Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]
Keywords: Anti-H3K27me3S28p, Anti-trimethyl-HIST2H3A, Anti-trimethyl-Histone H3.2, Anti-trimethyl-Histone H3/o, Anti-trimethyl-Histone H3/m
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-I84

Properties

Application: ChIP, IHC, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, c.elegans (Expected: rat, chicken, Xenopus, Drosophila, plant)
Immunogen: synthetic trimethylated/phosphorylated peptides surrounding Lysine 27 and Serine 28 of human Histone H3.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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