Applications: , Suitable for use in Western Blot, Dot Blot, ChIP. Other applications not tested. Recommended Dilution: Western Blot: 1:5000-1:10,000 dilution of this antibody was used to detect trimethylated-Histone H3 (Lys4) in HeLa nuclear acid extracts., Dot Blot: 1:10,000 , Optimal dilutions to be determined by...

Peptide is used to block Tri-MethylHistone H3 (Lys4) Rabbit mAb and Tri-Methyl-Histone H3 (Lys4) Antibody reactivity in immunohistochemistry protocols. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. Originally thought to function as a static...

The methylation of specific histone lysines controls aspects of short- and long-term transcriptional regulation, in addition to the propagation of bulk chromosome structure and stability. Methylation of histone H3 K27 is also involved in transcriptional silencing of human polycomb target genes and earliest chromatin...

The methylation of specific histone lysines controls aspects of short- and long-term transcriptional regulation, in addition to the propagation of bulk chromosome structure and stability. Methylated histone H3 K27 is also involved in transcriptional silencing of human polycomb target genes and earliest chromatin...