BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.
Immunogen: synthetic phospho-peptide. Immunogen for A300-007A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1387 according to the numbering given in entry NP_009225.1.
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Kat #: A300-007A
Menge: 100 µlBuy Bulk
Preis: 366 €
UniProt ID: P38398 (Protein knowledgebase)
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Schlagworte:
EC=6.3.2.-, Anti-phospho-BRCA1, Anti-phospho-BRCA (pS1387), Anti-phospho-Breast Cancer Gene 1, Anti-phospho-Breast Cancer 1, Anti-phospho-Early Onset, Anti-phospho-Breast-Ovarian Cancer Susceptibility, antibody, antibodies, Antikörper Loading ...
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| Weitere Produkte für dieses Protein:Antibodies
- Anti-BRCA1, Kat #: A300-000A
- Anti-BRCA1, Kat #: A301-377A
- Anti-BRCA1, Kat #: A301-378A
- Anti-BRCA1 (Ab-1423), Kat #: ABD-8B7030.50
- Anti-BRCA1 (Ab-1524), Kat #: ABD-8B7031.50
- Anti-BRCA1 (Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Cancer Type 1 Susceptibility Protein, BRCC1, Breast Ovarian Cancer Susceptibility, Papillary Serous Carcinoma of the Peritoneum, PSCP, RING Finger Protein 53, RNF53), Kat #: B2709-06A.50
- Anti-BRCA1 (Breast Cancer Antigen, Early Onset Breast Ovarian Cancer Susceptibility Protein 1), Kat #: B2709-01J.50
- Anti-BRCA1 (Breast Cancer Type 1 Susceptibility Protein, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PSCP, RING Finger Protein 53, RNF53), Kat #: B2709-01P.100
- Anti-BRCA1 (IHC), Kat #: IHC-00278
- Anti-BRCA1 (N-term), Kat #: WA-AP17140a
- more
Primers
Products for: BRCA1 - breast cancer type 1 susceptibility protein
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