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Anti-phospho-4E Binding Protein 1, (Thr37/46) (Protein...

Item number: 0004-18J.100

When bound to eIF4E, 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation. Upon hyperphosphorylation of 4E-BP1 this interaction is disrupted and cap-dependent translation is activated (1). Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity (2,3). Multiple 4E-BP1 residues are...

Keywords:	Anti-phospho-4E-BP1, Anti-phospho-PHAS-I, Anti-phospho-Eif4ebp1, Anti-phospho-eIF4E-binding protein 1,...
Application:	FC, ICC, IF, IHC, WB
Host:	Rabbit
Species reactivity:	drosophila, human, monkey, mouse, rat

757.00€ *

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