- Search results for P1001-29N.100
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63 products were found matching "P1001-29N.100"!
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Item number: P1001-26N.100
Human p53 is a tumor suppressor protein which is mutated in many cancers. p53 expression has been linked to apoptosis caused by DNA-damaging agents and may have a role in cell-mediated cytotoxicity. Applications: Suitable for use in Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not...
Application: | FC, IHC, WB |
Host: | Mouse |
Species reactivity: | human |
531.00€
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Item number: P1001-29C.100
p53 tumor suppressor gene mutations are one of the most common genetic alterations in human tumors, including lymphomas. Altering or inactivating p53 by mutation or reaction with oncogenes or viruses may cause depletion of p53, or conversion of p53 from a tumor suppressor gene to a transforming oncogene. The nuclear...
Application: | ELISA, IHC, IP, WB |
Host: | Mouse |
Species reactivity: | bovine, chicken, hamster, human, monkey, mouse, rat |
765.00€
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Item number: P1001-39N.100
Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at...
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
477.00€
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Item number: P1001-26N1.100
Human p53 is a tumor suppressor protein which is mutated in many cancers. p53 expression has been linked to apoptosis caused by DNA-damaging agents and may have a role in cell-mediated cytotoxicity. Applications: Suitable for use in Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not...
Application: | FC, IHC, WB |
Host: | Mouse |
Species reactivity: | human |
621.00€
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Item number: P1001-26N5.100
p53 is a 53kD protein that forms tetramers and functions as a tumor suppressor and transcriptional activator of genes that inhibit growth and/or invasion, cell cycle checkpoint after irradiation, DNA repair, apoptotic induction, signal transduction, and cell adhesion. This protein is localized to the nucleus when...
Application: | ELISA, WB |
Host: | Mouse |
Species reactivity: | human |
From 431.00€
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Item number: P1001-20G.100
The NADPH oxidase generates superoxide in phagocytic cells. It is important for immunity and its deficiency leads to chronic granulomatous disease (CGD). p40-phox is a newly isolated cytosolic component of the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase that copurifies with p67-phox. Preliminary...
Keywords: | Anti-p40phox |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human |
675.00€
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Item number: P1001-23B.100
The F-box protein p45SKP2 is the substrate-targeting subunit of the protein ligase SCFSKP2 and is frequently overexpressed in transformed cells. Expression of p45SKP2 in quiescent fibroblasts promotes p27Kip1 degradation, allows the generation of cyclin-A-dependent kinase activity, and allows entry into the S phase...
Application: | ELISA, IP, WB |
Host: | Mouse |
Species reactivity: | human |
909.00€
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Item number: P1001-24J.100
Neutrophil cytosolic factor 1 (NCF1) is a 47kD cytosolic subunit of the multi-protein complex known as NADPH oxidase. Expression of NCF1 is restricted to granulocytes, monocytes and B lymphocytes. Defects in NCF1 have been reported to be a cause of autosomal recessive chronic granulomatous disease. Applications:...
Keywords: | Anti-NCF-1, Anti-NCF-47K, Anti-p47-phox, Anti-Nox organizer 2, Anti-Nox-organizing protein 2, Anti-Neutrophil cytosol... |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human, mouse, swine |
675.00€
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Item number: P1001-25D.100
The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro (2,3). DNA...
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
757.00€
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Item number: P1001-25F.100
The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro (2,3). DNA...
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human, monkey |
757.00€
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Item number: P1001-25P.100
P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability....
Application: | IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
662.00€
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Item number: P1001-25Q.100
53BP1 binds to the tumor suppressor protein p53 and has a potential role in DNA damage responses. Small interfering RNA (siRNA) directed against 53BP1 in mammalian cells to demonstrated that 53BP1 is a key transducer of the DNA damage checkpoint signal. 53BP1 was required for p53 accumulation, G2-M checkpoint...
Application: | ICC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
644.00€
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