CDK4 (cyclin-dependent kinase 4) is a 34kD member of the CMGC Ser/Thr protein kinase family of enzymes. Within the cell, pRb/retinoblastoma protein is normally unphosphorylated and suppresses cell growth at the G1 stage of the cell cycle. When mitosis is required, CDK4 is phosphorylated, forms a complex with cyclin...

Source:, Recombinant corresponding to aa16-271 of human CDK4 (43G to 47G were replaced to EE and T172A)/Cyclin D1, fused to His-Tag at C-terminal (CDK4), co-expressed in a Baculovirus infected Sf9 cell expression system (NM_000075/NM_053056). Applications: Suitable for use in three dimensional structure studies....

Recommended Secondary Reagents: F(ab')2 rabbit anti-mouse IgG HRP , Applications: Immunohistochemistry (frozen), Immunoprecipitation, Western Blot , Optimal working dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and...

Trinactin is a macrotetrolide antibiotic produced by Streptomyces and an ionophore for monovalent cations, such as sodium, potassium, and ammonium. It is commonly used to facilitate the movement of monovalent cations through natural and artificial lipid membranes.Formal Name:...