- Search results for C2574-81
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13 products were found matching "C2574-81"!
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Item number: C2574-85.20
Source:, Recombinant corresponding to aa16-271 of human CDK4 (43G to 47G were replaced to EE and T172A)/Cyclin D1, fused to His-Tag at C-terminal (CDK4), co-expressed in a Baculovirus infected Sf9 cell expression system (NM_000075/NM_053056). Applications: Suitable for use in three dimensional structure studies....
Keywords: | CDK4, PSK-J3, EC=2.7.11.22, Cyclin-dependent kinase 4, Cell division protein kinase 4 |
Origin: | human |
955.00€
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Item number: Cay25748-1
Tropifexor is an agonist of farnesoid X receptors (FXR). It enhances the interaction between the human FXR ligand binding domain and the steroid receptor coactivator 1 (SRC-1) peptide in a homogeneous time-resolved fluorescence (HTRF) coactivator interaction assay (EC50 = 0.2 nM). It increases expression of the FXR...
Keywords: | LJN452,... |
Application: | Farnesoid X receptor (FXR) agonist |
CAS | 1383816-29-2 |
MW: | 603.6 D |
From 125.00€
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Item number: C2574-10.100
Recommended Secondary Reagents: F(ab')2 rabbit anti-mouse IgG HRP , Applications: Immunohistochemistry (frozen), Immunoprecipitation, Western Blot , Optimal working dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and...
Application: | IHC, IP, WB |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
913.00€
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Item number: C2574-05.500
A family of proteins designated as cdks are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. Applications: Suitable for use in Immunofluorescence,...
Application: | IF, IP, WB |
Host: | Mouse |
Species reactivity: | human, mouse, swine, rat |
906.00€
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Item number: C2574-35.100
Applications: , Suitable for use in ELISA, Western Blotting, and Immunoprecipitation. Other applications have not been tested. Recommended Dilution: ELISA: 1:500-1:2000, Western Blotting: 1:200-1:500, , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term...
Application: | ELISA, IP, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
946.00€
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Item number: C2574-53.10
Cyclin-dependent kinase 4 combines with the protein cyclin D to form a protein complex that promotes the passage of cells through the G1 checkpoint in the cell growth cycle. This cellular activity is regulated by the protein p16 produced by p16INK4a. Normally, p16 controls cell growth by inhibiting the activity of...
MW: | 38.00 kD |
From 598.00€
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Item number: C2574-54.50
Cyclin dependent kinases (CDK's) are kinases that interact with cyclins and regulate cell division. There is evidence that phosphorylation of the C-terminal region of Rb by Cdk4/6 initiates successive intramolecular interactions between the C-terminal region and the central pocket. The initial interaction displaces...
Application: | IHC, WB |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
834.00€
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Item number: C2574-55.50
The prototype of the cdk family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. Applications: Suitable for use in Western Blot, Immunofluorescence, Immunoprecipitation and Kinase Assay. Other applications not tested. Recommended...
Application: | IF, IP, WB |
Host: | Mouse |
Species reactivity: | human, mouse, swine, rat |
796.00€
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Item number: C2574-57.1
Cyclin-dependent kinase 4 (Cdk4) is a 34kD catalytic subunit of the protein kinase complex and belongs to the Ser/Thr protein kinase family. Cdk4 forms a complex with D-type cyclins and may regulate cell growth during G1 phase of the cell cycle. Cdk4 also associates with Cdk inhibitor p16 that down-regulates Cdk4...
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
924.00€
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Item number: C2574-05G.100
Cdk4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. Cdk4 is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1/S phase,...
Application: | ICC, WB |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
540.00€
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Item number: C2574-06C.100
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase...
Application: | ELISA, IF, WB |
Host: | Mouse |
Species reactivity: | human |
699.00€
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Item number: C2574-30A.100
CDK4 (cyclin-dependent kinase 4) is a 34kD member of the CMGC Ser/Thr protein kinase family of enzymes. Within the cell, pRb/retinoblastoma protein is normally unphosphorylated and suppresses cell growth at the G1 stage of the cell cycle. When mitosis is required, CDK4 is phosphorylated, forms a complex with cyclin...
Keywords: | EC=2.7.11.22, Anti-Cyclin-dependent kinase 4, Anti-Cell division protein kinase 4 |
Application: | WB |
Host: | Goat |
Species reactivity: | human, mouse |
991.00€
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