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Antikörper Treffer 1
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Name/Antigen KLON WIRT TYP ISOTYP SPEZ. REAKT. FORMAT ANWENDUNG HERSTELLER KAT # MENGE PREIS










Anti-​acetyl-​p53 (Lys386)
Rabbit
> sec. Ab
Pab IgG
human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified IHC
IF
ELISAErklärungen der Abkürzungen ansehen.
AAT Bioquest
Icon Datasheet
manual
ABD-​8D0017.50 50 µg

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195 €
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Anti-acetyl-p53 (Lys386)


Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-​activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-​dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-​2 expression. Implicated in Notch signaling cross-​over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-​inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-​mediated apoptosis.
Immunogen: synthetic peptide


Datenblatt ansehen
Manual

Kat #: ABD-8D0017.50


Menge:
50 µg

Buy Bulk


Preis:
195 €

UniProt ID: P04637 (Protein knowledgebase)
Geninformationen: GeneID 7157

Antikörper-Konjugations-Kits

Schlagworte:
Anti-​P53, Anti-​TP53, Anti-​Antigen NY-​CO-​13, Anti-​Phosphoprotein p53, Anti-​Tumor suppressor p53, Anti-​Cellular tumor antigen p53, antibody, antibodies, Antikörper

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