Kontakt 0800-2466651 DE | EN Merkliste Login Warenkorb
Reset
Suche
zurück

Anti-acetyl-p53 (Lys386)

ART NR.: ABD-8D0017.50 (50 µg)

Hersteller: AAT Bioquest

Datenblatt



Manual



MSDS

Anwendungen: IHC, IF, ELISA

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: synthetic peptide

Lagerung: +4°C

Versand: +4°C

UniProt ID: P04637 | Suche mit UniProt ID

Gene ID: Gene ID 7157 | Suche mit Gene ID

KEGG ID: K04451 | Suche mit KEGG ID

Schlagworte: Anti-P53, Anti-TP53, Anti-Antigen NY-CO-13, Anti-Phosphoprotein p53, Anti-Tumor suppressor p53, Anti-Cellular tumor antigen p53

ABD-8D0017.50

50 µg

216 €

In Warenkorb aufnehmen


Bemerkungen: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.

Spezifikationen

aat_bioquest_datasheet_parse.php?nr=ABD-8D0017.50&ak=1
Loading Loading ...

Verwandte Produkte

    Products for: TP53, P53 - tumor protein p53

    Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.



    Two is MUCH better than oneCut Your Validation Time in HalfArigo Antibody Duos

     Recombinant Monoclonal Antibodies from a Non-Animal SourceAntibody GuaranteeEasy Antibody Conjugation alle Treffer anzeigen (222 INFOS)

     


    Forschungsprodukte im Fokus
     
    Produkte
    Service
    Company
    € 10 Gutschein sichern