Anti-Valosin Containing Protein, CT (VCP, Valosin-containing Protein, 15S Mg(2+)-ATPase p97 Subunit,

Anti-Valosin Containing Protein, CT (VCP, Valosin-containing Protein, 15S Mg(2+)-ATPase p97 Subunit,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
V1035-20E-PE.200 200 µl - -

3 - 19 business days*

993.00€
 
Valsolin Containing Protein (VCP) is a member of a family that includes putative ATP-binding... more
Product information "Anti-Valosin Containing Protein, CT (VCP, Valosin-containing Protein, 15S Mg(2+)-ATPase p97 Subunit,"
Valsolin Containing Protein (VCP) is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. p97/VCP (valosin containing protein) belongs to the AAA ATPase family, predicted molecular weight 97kD. VCP, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. Valosin-containing protein (VCP or p97) belongs to the AAA (ATPase associated activities) family and acts as a molecular chaperone to a wide variety of cellular activities. Some of these activities include the alteration of both nuclear and mitotic golgi membranes, ubiquitin-proteasome dependent protein degradation, regulation of the NF-kappa b pathway, and extraction of membrane proteins. VCP has been shown to contain a substrate binding domain (N) and two conserved ATPase domains (D1 and D2). The three dimensional structure of VCP resembles that of a cylinder with the D1 and D2 stacked upon one another in a homo-hexameric ring formation. VCP is involved in the formation of neuronal inclusion bodies in neurodegenerative disease such as Parkinson's Disease. , Applications: , Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-VCP, Anti-TER ATPase, EC=3.6.4.6, Anti-Valosin-containing protein, Anti-15S Mg(2+)-ATPase p97 subunit, Anti-Transitional endoplasmic reticulum ATPase
Supplier: United States Biological
Supplier-Nr: V1035-20E-PE

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide selected from the C-terminal region of human VCP (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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