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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A303-527A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A303-527A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments... more
Product information "Anti-VPS11"
Protein function: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203). Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes (PubMed:21148287). Involved in the retrograde Shiga toxin transport (PubMed:23593995). [The UniProt Consortium]
Keywords: | Anti-VPS11, Anti-PP3476, Anti-hVPS11, Anti-RNF108, Anti-RING finger protein 108, Anti-Vacuolar protein sorting-associated protein 11 homolog |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A303-527A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: orangutan, gorilla, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A303-527A maps to a region between residue 550 and 600 of human Vacuolar Protein Sorting 11 using the numbering given in entry NP_068375.3 (GeneID 55823). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K20179 | Matching products |
UniProt ID : | Q9H270 | Matching products |
Gene ID | GeneID 55823 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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