- Search results for Cay13724-200
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8 products were found matching "Cay13724-200"!
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Item number: Cay23724-100
6-Aminocaproic acid is an inhibitor of the plasmin activating enzymes streptokinase, fibrinokinase, and urokinase (IC50s = ~8 µM for all in an enzyme assay). It is selective for plasmin activating enzymes over trypsin (IC50 = >500 µM). 6-Aminocaproic acid inhibits in vitro plasmin activation and fibrinolysis in a...
Keywords: | EACA, NSC 212532, NSC 26154, NSC 400230, epsilon-Aminocaproic Acid, 6-amino-hexanoic acid |
Application: | Plasmin activating enzyme (streptokinase, fibrinokinase, urokinase) inhibitor |
CAS | 60-32-2 |
MW: | 131.2 D |
From 77.00€
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Item number: Cay13224-25
Neurodazine induces neuronal differentiation in skeletal muscle cells. In mouse C2C12 myoblasts, neurodazine (2 µM for seven days) upregulated the expression of neuron-specific enolase (NSE), neurofilament 200 (NF200), synapsin, and other neuronal markers. Neurodazine similarly upregulated NSE and NF200 in human...
Keywords: | 2-[5-(3-chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole |
Application: | Metabolic studies |
CAS | 937807-66-4 |
MW: | 456.9 D |
From 163.00€
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Item number: Cay13200-5
G-418 is an aminoglycoside antibiotic. It is active against T. thermophila (IC50 = 10 µM). It inhibits the 80S ribosome and protein elongation during translation in a cell-free assay when used at a concentration of 2 nM. G-418 is used in molecular biology as a selective agent in cell lines or plasmids containing the...
Keywords: | Geneticin,... |
Application: | Antibiotic |
CAS | 108321-42-2 |
MW: | 692.7 D |
From 76.00€
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Item number: Cay13204-1
Sonic hedgehog (Shh) is the most widely characterized of the three vertebrate Hedgehog homologs, and is essential for proper embryonic development. Shh binds to its receptor, Patched (Ptch1), resulting in the de-repression of Smoothened. This leads to the activation of Gli2, which regulates the transcription of...
Keywords: | N-[(4-chlorophenyl)methyl]-5,12-dioxo-2R-phenyl-1-oxa-4-azacyclododec-8E-ene-6S-acetamide |
Application: | Shh inhibitor |
CAS | 1132653-79-2 |
MW: | 455 D |
456.00€
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Item number: Cay14720-500
15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 (Cay-14010) formed by 15-hydroxy prostaglandin dehydrogenase (15-PGDH). Unlike PGE2, 15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 2.6 and 15 µM, respectively) or induce adenylate cyclase activity...
Keywords: | 15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 26441-05-4 |
MW: | 350.5 D |
From 88.00€
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Item number: Cay23704-25
P22077 is a dual inhibitor of the deubiquitylating enzymes ubiquitin-specific protease 7 (USP7) and USP47 (EC50s = 8.01 and 8.74 µM, respectively, in a fluorescence-based enzyme assay). It is selective for USP7 and USP47 over other USPs and proteases with EC50 values greater than 50 µM. P22077 (25 µM) induces the...
Keywords: | 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
Application: | USP7 / USP47 inhibitor |
CAS | 1247819-59-5 |
MW: | 315.3 D |
From 60.00€
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Item number: Cay23700-25
Nepafenac is a prodrug form of amfenac, a non-steroidal anti-inflammatory drug (NSAID) and an inhibitor of COX-1 and COX-2. Nepafenac is an inhibitor of prostaglandin (PG) synthase 1 (IC50 = 64.3 µM) that inhibits the production of PGs in isolated rabbit iris/ciliary body. It also reduces protein and PGE2...
Keywords: | AHR 9434, AL 6515, 2-amino-3-benzoyl-benzeneacetamide |
Application: | COX inhibitor |
CAS | 78281-72-8 |
MW: | 254.3 D |
From 60.00€
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Item number: Cay24200-10
Vonoprazan is a selective, reversible, and potassium-competitive proton pump inhibitor that inhibits gastric H+/K+ ATPase (IC50 = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration of 10 µM. It maintains its inhibitory effect in both weakly acidic (pH 6.5) and neutral (pH 7.5)...
Keywords: | TAK-438, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine, 2-butenedioate |
Application: | Proton pump inhibitor |
CAS | 1260141-27-2 |
MW: | 461.5 D |
From 60.00€
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