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Anti-Ubiquitin Activating Enzyme 6 (Ubiquitin-like Modifier-activating Enzyme 6, UBA6, E1-L2, FLJ10808, FLJ23367, Monocyte Protein 4, MOP4, MOP-4, Ubiquitin-activating Enzyme E1-like Protein 2, UBE1L2)

ART NR.: U1002-01.100 (100 µg)

Hersteller: USBio

Datenblatt

Anwendungen: IHC, WB

Format: affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: Synthetic peptide corresponding to aa775-825 of human UBE1L2/MOP-4.

Lagerung: -20°C

Versand: +4°C

UniProt ID: A0AVT1 | Suche mit UniProt ID

Gene ID: Gene ID 55236 | Suche mit Gene ID

KEGG ID: K10699 | Suche mit KEGG ID

Schlagworte: Anti-Monocyte protein 4, Anti-Ubiquitin-activating enzyme 6, Anti-Ubiquitin-like modifier-activating enzyme 6, Anti-Ubiquitin-activating enzyme E1-like protein 2

U1002-01.100

100 µg

545 €

In Warenkorb aufnehmen


Bemerkungen: Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility. [The UniProt Consortium]

Spezifikationen

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