Anti-UNG1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-FV0 100 µg - -

6 - 10 business days*

684.00€
 
Anti-UNG1 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-UNG1"
Anti-UNG1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with UNG1 from other sources has not been determined. Protein function: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR, however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. [The UniProt Consortium]
Keywords: Anti-ULK1, Anti-ATG1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1 homolog, Anti-Serine/threonine-protein kinase ULK1
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-FV0

Properties

Application: ELISA, IHC, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: 14 amino acid synthetic peptide from near the C-terminus of human UNG1.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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