25 products were found matching "T9162-01"!

Applications:, Suitable for use in Neutralization, ELISA and Western Blot. Other applications not tested. Recommended Dilution: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of human sTNFR1 (0.3ug/ml), a concentration of 0.9-1.1ug/ml is required. ELISA: To detect human sTNFR1...

TRADD [tumor necrosis factor receptor type 1-associated (TNFR1) death domain protein] is a death domain containing adaptor molecule that interacts with TNFR1:TNFRSF1A and mediates programmed cell death signaling and NF-kB activation (reviewed in Feng, 2005). TRADD binds adaptor protein TRAF2, reduces the recruitment...

TNFR1 is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. Induction of cytotoxicity and other functions are mediated largely via TNFR1. This antibody is an agonistic antibody. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other...

TNF-R I is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha: Induction of cytotoxicity and other functions are mediated largely via TNF-R I. Applications: Suitable for use in ELISA, Flow Cytometry and Immunohistochemistry. Other applications not tested....

Applications: , Suitable for use in Flow Cytometry, Immunohistochemistry and Functional Studies. Other applications have not been tested. , Recommended Dilutions: Immunohistochemistry (Frozen): 1:150 , Functional Studies: Neutralizes TNF-induced cytotoxicity on 4937 MCF-7, HeLa, and L929 cells, TNF-induced MHC...

The immunoregulatory cytokine tumor necrosis factor alpha (TNFa) recognizes two cell surface receptors. TNF-R1 (also known as CD120a) has an apparent molecular mass of 55/60kD and is constitutively expressed on all nucleated cells, whereas TNF R2 (also known as CD120b) with an apparent molecular mass of 75/80kD, is...

Tumor necrosis factor receptor 1 (TNFR1), a potent cytokine, elicits a broad spectrum of biologic responses which are mediated by binding to a cell surface receptor. Its gene is located on 12p13. The coding region and the 3-prime untranslated region of TNFR1 are distributed over 10 exons. There are 2 different...

TNF-R I is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha: Induction of cytotoxicity and other functions are mediated largely via TNF-R I. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other...

The immunoregulatory cytokine tumor necrosis factor alpha (TNFa) recognizes two cell surface receptors. TNF-R1 (also known as CD120a) has an apparent molecular mass of 55/60kD and is constitutively expressed on all nucleated cells, whereas TNF R2 (also known as CD120b) with an apparent molecular mass of 75/80kD, is...

Tumor necrosis factor alpha (TNFalpha), also known as cachectin, is a 17.5kD, 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells,...

Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:100-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at...

The immunoregulatory cytokine tumor necrosis factor alpha (TNFa) recognizes two cell surface receptors. TNF-R1 (also known as CD120a) has an apparent molecular mass of 55/60kD and is constitutively expressed on all nucleated cells, whereas TNF R2 (also known as CD120b) with an apparent molecular mass of 75/80kD, is...