NK1R (Neurokinin-1 receptor), gene name TACR1 (tachykinin receptor-1), is an 80kD 7-transmembrane glycoprotein receptor for the proinflammatory tachykinin neuropeptide, substance P. NK1R is constitutively or inducibly expressed on a wide variety of cells, including monocytes, macrophages, microglia, lymphocytes,...

Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral...

Applications: , Suitable for use in ELISA, Western Blotting, Immunohistochemistry, Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blotting: 1:1000-1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for...

Thioredoxins are a group of ~12kD redox proteins that mediate numerous cytosolic processes in all cells. Human thioredoxin can be exported out of the cell where it has additional functions including the ability to stimulate cell growth. Recombinant yeast Thioredoxin is a single, non-glycosylated, polypeptide chain...

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract many smooth muscles. Tachykinin-3 is a secreted protein and its expression during pregnancy is confined to the outer syncytiotophoblast of the placenta. Plasma concentrations of...