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Anti-TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily Member 1A, Tumor Necrosis Factor Receptor 1, TNF-R1, Tumor Necrosis Factor Receptor Type I, TNF-RI, TNFR-I, p55, p60, CD120a, TNFAR, TNFR1) (APC)

ART NR.: T9161-06P1.100 (100 tests)

Hersteller: USBio


Anwendungen: FC

Format: affinity purified

Klon: 11C57

Wirt: Mouse

Isotyp: IgG1

Reaktivität: human

Immunogen: E.coli-derived, recombinant human tumor necrosis factor receptor I (Accession # NP_001056) extracellular domain.

Lagerung: +4°C

Versand: +4°C

UniProt ID: P19438 | Suche mit UniProt ID

Gene ID: Gene ID 7132 | Suche mit Gene ID

KEGG ID: K03158 | Suche mit KEGG ID

Schlagworte: Anti-TBPI, Anti-Tumor necrosis factor receptor 1, Anti-Tumor necrosis factor receptor type I, Anti-Tumor necrosis factor-binding protein 1, Anti-Tumor necrosis factor receptor superfamily member 1A



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Bemerkungen: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. [The UniProt Consortium]


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