Anti-TGFB2 (TGFB2, Transforming growth factor beta-2, BSC-1 cell growth inhibitor, Cetermin, Gliobl

Anti-TGFB2 (TGFB2, Transforming growth factor beta-2, BSC-1 cell growth inhibitor, Cetermin, Gliobl
Item number Size Datasheet Manual SDS Delivery time Quantity Price
031282.100 100 µl - -

3 - 19 business days*

728.00€
 
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines,... more
Product information "Anti-TGFB2 (TGFB2, Transforming growth factor beta-2, BSC-1 cell growth inhibitor, Cetermin, Gliobl"
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000, Western Blot: 1:500~16000, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: 031282

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 220ct16.4.3.1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: TGFB2 Mab is generated from mouse immunized with TGFB2 recombinant protein.
Purity: Ascites
Format: Ascites

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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