10 products were found matching "BPS-25317"!

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed...

RbAp48 (UniProtKB/Swiss Prot entry Q09028) is a component of several complexes which regulate chromatin metabolism. These include (1) the chromatin assembly factor 1 (CAF 1) complex, which is required for chromatin assembly following DNA replication and DNA repair, (2) the core histone deacetylase (HDAC) complex,...

Set9 (UniProtKB/Swiss Prot entry Q8WTS6) is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deacetylation of H3 by the NuRD complex and impairs Suv39h1 mediated...

SETD1A (UniProt/Swiss Prot entry O15047) is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional...

SETD1B (UniProt/Swiss Prot entry Q9UPS6) is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional...

SETD8 (UniProtKB/Swiss Prot entry Q9NQR1) is a histone methyl transferase that specifically monomethylates Lys 20 of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression en is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by...

SirT1 (UniProtKB/Swiss Prot entry Q96EB6) is a NAD dependent deacetylase, which regulates processes such as apoptosis and muscle differentiation by the deacetylation of key regulatory proteins. Deacetylation of lysine 382 of p53/TP53 by Sirt1 impairs its ability to induce the proapoptotic program and modulate cell...

TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence called the TATA box. This DNA sequence is found approximately 30 base pairs upstream of the transcription start site in 10 20% of eukaryotic gene promoters. TBP is a subunit of the eukaryotic transcription factor TFIID....

DNMT2 (UniProtKB/Swiss Prot entry O14717) belongs to the family of DNA cytosine methyltransferases. DNMT2, however, lacks the large N terminal regulatory domain common to other eukaryotic methyltransferases and does not methylate CpG in genomic DNA. Instead, it specifically methylates cytosine 38 in the anticodon...

PHC2 (UniProtKB/Swiss Prot entry Q8IXK0) is a component of a Polycomb group (PcG) multiprotein PRC1 like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification...