Anti-SMARCA3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-229A-T	20 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-229A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic... more

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Product information "Anti-SMARCA3"

Protein function: Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters. These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. [The UniProt Consortium]

Keywords:	Anti-HLTF, Anti-HIP116, Anti-HIP116A, EC=3.6.4.-, EC=2.3.2.27, Anti-RING finger protein 80, Anti-Helicase-like transcription factor, Anti-Sucrose nonfermenting protein 2-like 3, Anti-RING-type E3 ubiquitin transferase HLTF
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-229A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide. The epitope recognized by A300-229A maps to a region between residues 900 and 950 of human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily a, member 3 using the numbering given in entry NP_620636.1 (GeneID 6596).
Format:	Antigen Affinity Purified