Anti-SF3B3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-508A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-508A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B... more

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Product information "Anti-SF3B3"

Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome (PubMed:10490618, PubMed:10882114, PubMed:27720643, PubMed:28781166). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077). [The UniProt Consortium]

Keywords:	Anti-SF3B3, Anti-SAP 130, Anti-STAF130, Anti-SF3b130, Anti-KIAA0017, Anti-Splicing factor 3B subunit 3, Anti-Spliceosome-associated protein 130, Anti-Pre-mRNA-splicing factor SF3b 130 kDa subunit
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-508A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: zebrafish, bovine)
Immunogen:	synthetic peptide. The epitope recognized by A302-508A maps to a region between residue 1167 and 1217 of human splicing factor 3b, subunit 3 using the numbering given in entry NP_036558.3 (GeneID 23450).
Format:	Antigen Affinity Purified