Name/Antigen	KLON	WIRT	TYP	ISOTYP	SPEZ. REAKT.	FORMAT	ANWENDUNG	HERSTELLER	KAT #	MENGE	PREIS
Anti-SET7 (IHC)		Rabbit > sec. Ab	Pab	IgG	human	antigen affinity purified	IHC	Bethyl	IHC-00616	100 µl Buy Bulk	399 €
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro. Immunogen: The epitope recognized by IHC-00616 maps to a region between residue 316 and 366 of human SET domain containing (lysine methyltransferase) 7 using the numbering given in entry NP_085151.1 (GeneID 80854). Datenblatt ansehen Kat #: IHC-00616 Menge: 100 µl Buy Bulk Preis: 399 € UniProt ID: Q8WTS6 (Protein knowledgebase) Geninformationen: GeneID 80854 Antikörper-Konjugations-Kits Schlagworte: Anti-SETD7, Anti-SET7/9, EC=2.1.1.43, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-SET domain-containing protein 7, Anti-Histone H3-K4 methyltransferase SETD7, Anti-Histone-lysine N-methyltransferase SETD7, antibody, antibodies, Antikörper Loading ... zurück	Weitere Produkte für dieses Protein: Antibodies Anti-SET7, Kat #: A301-747A Anti-SET7 (C-term), Kat #: WA-AP1194d Anti-SET7 (N-term), Kat #: WA-AP1194a Anti-SET7 (SET Domain Containing Protein 7, SET Domain-containing Protein 7, SET7/9, SET9, SETD7, FLJ21193, H3-K4-HMTase, H3 Lysine-4 Specific, Histone H3 K4 Methyltransferase, Histone H3-K4 Methyltransferase, Histone H3 Lysine 4 Specific Methyltransferas, Kat #: S1012-22A.100 Anti-SET7 (SET9) (Center), Kat #: WA-AP1194c Anti-SET7, CT (Histone H3-K4 Methyltransferase SETD7, H3-K4-HMTase SETD7, SET Domain-Containing Protein 7, Set9, SET7/9, Lysine N-methyltransferase 7, Histone-lysine N-methyltransferase SETD7, KMT7, KIAA1717), Kat #: S1012-27C.100 Anti-SET7, ID (Histone H3-K4 Methyltransferase SETD7, H3-K4-HMTase SETD7, SET Domain-Containing Protein 7, Set9, SET7/9, Lysine N-methyltransferase 7, Histone-lysine N-methyltransferase SETD7, KMT7, KIAA1717), Kat #: S1012-27B.100 Anti-SET7, NT (Histone H3-K4 Methyltransferase SETD7, H3-K4-HMTase SETD7, SET Domain-Containing Protein 7, Set9, SET7/9, Lysine N-methyltransferase 7, Histone-lysine N-methyltransferase SETD7, KMT7, KIAA1717), Kat #: S1012-27A.100 Anti-Set7/9, Kat #: IMG-587 Anti-SET7/9, Kat #: Cay13731-1 more Enzymes & Proteins SET7/9 (human recombinant), Kat #: Cay10320-25 SET7/9 (human recombinant), Kat #: Cay10320-50 SET7/9 (human recombinant), Kat #: Cay10320-100 SET7/9 (human recombinant) Assay Enzyme, Kat #: Cay600492-25 SET7/9 (human recombinant) MT Assay Reagent, Kat #: Cay700271-1 Set7/9 (Sf9) Active human recombinant protein, Kat #: BPS-50019 Set7/Set9, active human recombinant protein, Kat #: BPS-51010 siRNA SETD7 predesign siRNA, Kat #: WA-RI14796 Plasmids/Vectors Human SETD7 cDNA Clone, Kat #: WA-DC14205 Chemicals & More SETD7 Over-expression Lysate, Kat #: WA-LY12102a ELISA and Assay Kits SET7/9 Methyltransferase Inhibitor Screening Assay Kit, Kat #: Cay700270-96 SET7/9 SAM-Screener(TM) Assay Kit (1920 wells), Kat #: Cay600490-1920 SET7/9 SAM-Screener(TM) Assay Kit (384 wells), Kat #: Cay600490-384 Peptides SET7 Antibody (C-term) Blocking Peptide, Kat #: WA-BP1194d SET7 Antibody (N-term) Blocking Peptide, Kat #: WA-BP1194a SET9 Antibody (Center) Blocking Peptide, Kat #: WA-BP1194c Relevant Pathways: Lysine degradation Products for: SETD7 - histone-lysine N-methyltransferase SETD7 [EC:2.1.1.43] Antibodies (12) ELISA and Assay Kits (3) Enzymes & Proteins (7) Peptides (3)

Anti-SET7 (IHC)

Rabbit
> sec. Ab

Pab

IgG

human

antigen affinity purified

IHC

Bethyl

IHC-00616

100 µl

Buy Bulk

399 €

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro.
Immunogen: The epitope recognized by IHC-00616 maps to a region between residue 316 and 366 of human SET domain containing (lysine methyltransferase) 7 using the numbering given in entry NP_085151.1 (GeneID 80854).

Datenblatt ansehen

Kat #:

IHC-00616

Menge:

100 µl

Buy Bulk

Preis:

399 €

UniProt ID: Q8WTS6 (Protein knowledgebase)
Geninformationen: GeneID 80854

Antikörper-Konjugations-Kits

Schlagworte:
Anti-SETD7, Anti-SET7/9, EC=2.1.1.43, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-SET domain-containing protein 7, Anti-Histone H3-K4 methyltransferase SETD7, Anti-Histone-lysine N-methyltransferase SETD7, antibody, antibodies, Antikörper

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