12 products were found matching "Cay13780-500"!

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Voriconazole-d3
Voriconazole-d3

Item number: Cay17803-500

Voriconazole-d3 is intended for use as an internal standard for the quantification of voriconazole (Cay-15633) by GC- or LC-MS. Voriconazole is a triazole antifungal agent and a derivative of fluconazole (Cay-11594). It is active against a variety of yeast and fungi, including clinical isolates of A. flavus, A....
Keywords: VRC-d3, (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-4,4,4-d3-2-ol
Application: Internal standard
MW: 352.3 D
From 240.00€ *
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GSK2636771
GSK2636771

Item number: Cay17380-500

Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol at the 3 position to produce the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3). Class 1 PI3Ks are composed of a p110 catalytic subunit, of which there are four isoforms...
Keywords: 2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylic acid
Application: PIK3CB inhibitor
CAS 1372540-25-4
MW: 433.4 D
From 60.00€ *
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HDMAPP (ammonium salt)
HDMAPP (ammonium salt)

Item number: Cay13580-500

HDMAPP is a metabolite of the microbial dioxyxylulose-phosphate pathway, which is analogous to the isopentenyl pyrophosphate pathway in mammals. It is a protease-resistant and phosphatase-sensitive pyrophosphate produced by bacteria and plants. HDMAPP is a non-peptide ligand, also called a phosphoantigen, that binds...
Keywords: HMBPP, mono[(2E)-hydroxy-3-methyl-2-butenyl] ester diphosphoric acid, triammonium salt
Application: Microbial deoxyxylulose-phosphate pathway metabolite, TCR ligand
CAS 443892-56-6
MW: 313.2 D
From 102.00€ *
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Pyroxamide
Pyroxamide

Item number: Cay13870-50

Pyroxamide is an inhibitor of histone deacetylases (HDACs), including HDAC1 (IC50 = 0.1-0.2 µM). It induces growth suppression and cell death of certain types of cancer cells in culture.Formal Name: N1-hydroxy-N8-3-pyridinyl-octanediamide. CAS Number: 382180-17-8. Molecular Formula: C13H19N3O3. Formula Weight:...
Keywords: N1-hydroxy-N8-3-pyridinyl-octanediamide
Application: Histone deacetylases Inhibitor
CAS 382180-17-8
MW: 265.3 D
From 82.00€ *
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666-15
666-15

Item number: Cay30780-50

666-15 is an inhibitor of gene transcription mediated by cAMP-response-element-binding protein (CREB, IC50 = 81 nM in a cell-based reporter assay). It inhibits the growth of A549, MCF-7, MDA-MB-231, and MDA-MB-468 cells (GI50s = 0.47, 0.31, 0.073, and 0.046 µM, respectively). 666-15 (10 mg/kg per day, five days per...
Keywords: Compound 3i,...
Application: CREB-mediated gene transcription inhibitor
CAS 1433286-70-4
MW: 620.5 D
From 205.00€ *
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Anti-Transferrin Receptor Protein 1/CD71 (mouse) Rabbit Monoclonal   (Clone 179)
Anti-Transferrin Receptor Protein 1/CD71 (mouse) Rabbit...

Item number: Cay37080-50

Transferrin receptor (TfR1), also known as CD71, is a homodimeric transmembrane receptor for transferrin (Cay-32030) that facilitates iron delivery into cells and is encoded by TFRC in humans. It is composed of two TfR1 monomers, each containing a cytoplasmic tail, an internalization motif, a membrane-spanning...
Keywords: Anti-TR, Anti-TfR, Anti-CD71, Anti-Tfrc, Anti-TfR1, Anti-Trfr, Anti-Transferrin receptor protein 1
Application: IHC
Host: Rabbit
Species reactivity: mouse
From 176.00€ *
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CAY10580
CAY10580

Item number: Cay16835-500

Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It...
Keywords: 2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid
Application: EP4 receptor activator
CAS 64054-40-6
MW: 341.5 D
From 96.00€ *
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Anti-SET7/9 (FL)
Anti-SET7/9 (FL)

Item number: Cay13780-1

Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly (ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene...
Keywords: Anti-SETD7, Anti-SET7/9, Anti-SET7/9, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-H3-K4-HMTase SETD7, Anti-Lysine...
Application: WB
Host: Rabbit
Species reactivity: human, mouse
422.00€ *
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Butaprost
Butaprost

Item number: Cay13740-500

Butaprost, a structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2 receptors are expressed on human neutrophils and on respiratory, vascular, and uterine smooth muscle. Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind...
Keywords: 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester, TR 4979,...
Application: EP2 receptor agonist
CAS 69685-22-9
MW: 408.6 D
From 115.00€ *
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15-keto Prostaglandin E1
15-keto Prostaglandin E1

Item number: Cay13680-500

15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE1.Formal Name: (11alpha,13E)-11-hydroxy-9,15-dioxo-prost-13-en-1-oic acid. CAS Number: 22973-19-9. Synonyms: 15-keto PGE1. Molecular Formula: C20H32O5. Formula Weight: 352.5....
Keywords: 15-keto PGE1, 9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid
Application: Bioactive lipid assays
CAS 22973-19-9
MW: 352.5 D
From 88.00€ *
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15(S)-15-methyl Prostaglandin E1
15(S)-15-methyl Prostaglandin E1

Item number: Cay13730-500

15(S)-15-methyl Prostaglandin E1 (15(S)-15-methyl PGE1) is a metabolically stable synthetic analog of PGE1 (Cay-13010). In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.Formal Name:...
Keywords: 15(S)-15-methyl PGE1, 9-oxo-11alpha,15S-dihydroxy-15-methyl-prost-13E-en-1-oic acid
Application: Bioactive lipid assays
CAS 35700-26-6
MW: 368.5 D
From 125.00€ *
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Anti-HDAC7 (Phospho-Ser155)
Anti-HDAC7 (Phospho-Ser155)

Item number: Cay13500-1

Histone deacetylase 7 (HDAC7) is a thymus-specific, intracellular transcription factor belonging to the class IIa HDAC family. Reports suggest that dephosphorylation and nuclear localization of HDAC7 is promoted by myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+/CD8+...
Keywords: Histone Deacetylase 7
Application: WB
Host: Rabbit
Species reactivity: human
485.00€ *
Review