Anti-SET07, ID (Histone H4-K20 Methyltransferase, H4-K20-HMTase, SET Domain-containing Protein 8, PR/SET Domain-containing Protein 07, PR/SET07, PR-Set7, KMT5A, Histone-lysine N-methyltransferase SETD8, H4-K20-HMTase SETD8, Lysine N-methyltransferase 5A,
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Rabbit > sec. Ab |
Pab |
IgG |
human
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purified |
ELISA WB |
USBio
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S1012-28F.100
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100 µg Buy Bulk |
417 €

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Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. [The UniProt Consortium] Immunogen: Synthetic peptide selected from the Center region of human SETD8 (KLH).
Datenblatt ansehen
Kat #: S1012-28F.100
Menge: 100 µgBuy Bulk
Preis: 417 €
UniProt ID: Q9NQR1 (Protein knowledgebase) Geninformationen: GeneID 387893
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Schlagworte: EC=2.1.1.-, EC=2.1.1.43, Anti-SET domain-containing protein 8, Anti-N-lysine methyltransferase SETD8, Anti-PR/SET domain-containing protein 07, antibody, antibodies, Antikörper Loading ...
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- Anti-SET07 (Histone H4-K20 Methyltransferase, H4-K20-HMTase, SET Domain-containing Protein 8, PR/SET Domain-containing Protein 07, PR/SET07, PR-Set7, KMT5A, Histone-lysine N-methyltransferase SETD8, H4-K20-HMTase SETD8, Lysine N-methyltransferase 5A, PRSE, Kat #: S1012-28A.100
- Anti-SET07 (Histone H4-K20 Methyltransferase, H4-K20-HMTase, SET Domain-containing Protein 8, PR/SET Domain-containing Protein 07, PR/SET07, PR-Set7, KMT5A, Histone-lysine N-methyltransferase SETD8, H4-K20-HMTase SETD8, Lysine N-methyltransferase 5A, PRSE, Kat #: S1012-28B.100
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Peptides
Products for: SETD8 - histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43]
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