Anti-SET07 (Histone H4-K20 Methyltransferase, H4-K20-HMTase, SET Domain-containing Protein 8, PR/SET

Anti-SET07 (Histone H4-K20 Methyltransferase, H4-K20-HMTase, SET Domain-containing Protein 8, PR/SET
Item number Size Datasheet Manual SDS Delivery time Quantity Price
S1012-28E-Biotin.200 200 µl - -

3 - 19 business days*

993.00€
 
SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation... more
Product information "Anti-SET07 (Histone H4-K20 Methyltransferase, H4-K20-HMTase, SET Domain-containing Protein 8, PR/SET"
SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Immunohistochemistry: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-SETD8, Anti-KMT5A, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase SETD8, Anti-Lysine N-methyltransferase 5A, Anti-SET domain-containing protein 8, Anti-N-lysine methyltransferase SETD8
Supplier: United States Biological
Supplier-Nr: S1012-28E-Biotin

Properties

Application: ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant protein encoding full length human SET07.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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