7 products were found matching "R2031-38V3.100"!

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell...

Ribosomal protein S6 kinase 1 (RPS6K1) is the best characterized effector of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors (1,2). Nutrients and...

The 70kD ribosomal S6 kinase, p70S6K1, is a serine/threonine kinase that functions as a downstream target of the phosphatidylinositol 3-kinase (PI3K)/AKT and mitogen-activated protein (MAP) kinase signaling pathways. p70S6K1 mediates several effects of the PI3K/AKT pathway, including cellular transformation. The...

RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation....

Ribosomal protein L26 (RPL26) is a component of the 60S ribosomal subunit and is involved in translation (1,2). It was shown that RPL26 increases the translation of p53 mRNA by binding to its 5' untranslated region (UTR) after DNA damage. Studies found that overexpression of RPL26 enhances the binding of p53 mRNA to...

RIP1 belongs to the Ser/Thr protein kinase family and promotes apoptosis and activation of NF-kappaB. It associates with the intracellular domain of TNFRSF6. Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling. It plays a critical role in tumor necrosis factor-alpha...

Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:1,000. , Western Blot: Preliminary experiments in Human Brain and Heart lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). Optimal dilutions to...