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Anti-RNA Polymerase II

ART NR.: A300-653A (100 µl | 100 µg)

Hersteller: Bethyl

Datenblatt

Anwendungen: WB, IP

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human (expected: rat, zebrafish, X. tropicalis, bovine, dog, rabbit, swine, panda, orangutan, rhesus monkey, gorilla, chimpanzee, eukaryota, rhodophyta, brassicaceae, mouse-ear cress, soybean, barrel medic, castor bean, slime mold_1054147)

Immunogen: synthetic peptide. The epitope recognized by A300-653A maps to the C-terminal repeat of human RNA Polymerase II (GeneID 5430).

Lagerung: +4°C

Versand: +4°C

UniProt ID: P24928 | Suche mit UniProt ID

KEGG ID: K03006 | Suche mit KEGG ID

Schlagworte: Anti-POLR2, EC=2.7.7.6, Anti-POLR2A, EC=2.7.7.48, Anti-RNA polymerase II subunit B1, Anti-DNA-directed RNA polymerase II subunit A, Anti-DNA-directed RNA polymerase II subunit RPB1, Anti-RNA-directed RNA polymerase II subunit RPB1

A300-653A

100 µl (100 µg)

356 €

In Warenkorb aufnehmen


Bemerkungen: The RNA polymerase II subunit B1 (RPB1) is the largest subunit of the RNA polymerase II core complex. RNA polymerase II holoenzyme functions to transcribe DNA into messenger RNA in eukaryotes. RPB1 forms the DNA binding domain of the polymerase that forms a cleft that grabs the incoming DNA template to translocate the holoenzyme across the RNA-DNA hybrid. Alternate identifiers of RPB1 include DNA-directed RNA polymerase II subunit RPB1, DNA directed RNA polymerse II subunit A, DNA-directed RNA polymerase II largest subunit, POLR2A, RPO2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220, and MGC75453.

Spezifikationen

RNA Polymerase II Antibody

Rabbit anti-RNA Polymerase II Antibody, Affinity Purified
RNA Polymerase II AntibodyRNA Polymerase II AntibodyRNA Polymerase II Antibody
RNA Polymerase II AntibodyRNA Polymerase II AntibodyRNA Polymerase II Antibody

Gene and Protein Information

Citations

Garriga J., CDK9 inhibition strategy defines distinct sets of target genes BMC Res Notes. 2014 May 16;7:301. WB
PubMed: 24886624
Berlivet S, Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs. PLoS Genet. 2013 Dec;9(12):e1004018. ChIP
PubMed: 24385922
Lovén J, Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell. 2013 Apr 11;153(2):320-34. ChIP
PubMed: 23582323
Wu Y et al., Cyclin-dependent kinase 7/9 inhibitor SNS-032 abrogates FIP1-like-1 platelet-derived growth factor receptor ? and bcr-abl oncogene addiction in malignant hematologic cells. Clin Cancer Res. 2012 Apr 1;18(7):1966-78. WB
PubMed: 22447844
Schmutz I et al., Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock. PLoS One. 2011;6(6):e21325. WB
PubMed: 21712997
Pakala SB et al., TGF-?1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells. Oncogene. 2011 May 12;30(19):2230-41. WB, ChIP
PubMed: 21258411
Ghanta KS et al., MTA1 coregulation of transglutaminase 2 expression and function during inflammatory response. J Biol Chem. 2011 Mar 4;286(9):7132-8. ChIP, WB
PubMed: 21156794
Lucio-Eterovic AK et al., Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16952-7. WB
PubMed: 20837538
Pakala SB et al., MTA1 coregulator regulates LPS response via MyD88-dependent signaling. J Biol Chem. 2010 Oct 22;285(43):32787-92. ChIP, WB
PubMed: 20702415
Pakala SB et al., Regulation of NF-kappaB circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis. J Biol Chem. 2010 Jul 30;285(31):23590-7. WB, IP, ChIP
PubMed: 20519513
Schmutz I et al., The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors. Genes Dev. 2010 Feb 15;24(4):345-57. WB
PubMed: 20159955
Glover-Cutter K et al., TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II. Mol Cell Biol. 2009 Oct;29(20):5455-64. WB
PubMed: 19667075
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