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Anti-​Progranulin (human), clone PG359-​7
PG359-7 Mouse
> sec. Ab
Mab IgG1
kappa
human
Erklärungen der Abkürzungen ansehen.
purified ELISA
IHC
IP
WBErklärungen der Abkürzungen ansehen.
Adipogen
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AG-​20A-​0052-​C100

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100 µg

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264 €
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Anti-Progranulin (human), clone PG359-7


Recognizes human progranulin. Detects a band of about 90kDa by Western blot. Liquid. 0.2µm-​filtered solution in PBS, pH 7.4. Contains no preservatives. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
Immunogen: Recombinant human progranulin.
MW: 90 kD


Datenblatt ansehen

Kat #: AG-20A-0052-C100


Menge:
100 µg

Buy Bulk


Preis:
264 €

UniProt ID: P28799 (Protein knowledgebase)

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Schlagworte:
Proepithelin, PEPI, PC Cell-​derived Growth Factor, antibody, antibodies, Antikörper
Image Art AG-20A-0052 Adipogen Anti-​Progranulin (human), clone PG359-​7
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