25 products were found matching "P4076-11"!

Protein function: Within the IL18 receptor complex, does not mediate IL18- binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. [The UniProt Consortium]

Phosphorylation and dephosphorylation of cellular proteins are central steps in transducing extracellular signals to the cell nucleus. Phosphorylated epitopes may serve as docking sites for the assembly of protein complexes or may alter the 3-dimensional protein structure thus modulating enzymatic activity or the...

Protein phosphorylation is an important post-translational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently...

Protein phosphorylation is an important post-translational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently...

Phosphorylation and dephosphorylation of cellular proteins are central steps in transducing extracellular signals to the cell nucleus. Phosphorylated epitopes may serve as docking sites for the assembly of protein complexes or may alter the 3-dimensional protein structure thus modulating enzymatic activity or the...

Changes in the serine/threonine phosphorylation state of a protein in response to various external stimuli can have profound effects on cellular signal transduction, apoptosis and carcinogenesis. The reagents, including phosphorylated proteins, peptides, and antibodies against the phosphospecific amino acid, are...

Phosphorylation and dephosphorylation of cellular proteins are central steps in transducing , extracellular signals to the cell nucleus. Phosphorylated epitopes may serve as docking sites for , the assembly of protein complexes or may alter the 3-dimensional protein structure thus , modulating enzymatic activity or...

Human placental alkaline phosphatase is also known as Alkaline phosphatase Regan isozyme, Alkaline phosphatase, placental type or Placental alkaline phosphatase 1. Placental alkaline phosphatase is a 535aa ~67kD GPI-anchored transmembrane glycoprotein bearing a 22 amino acid signal peptide and a 29 amino acid...

Antibody to PLAP is useful in the identification of germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA). Applications: Suitable for use in ELISA and Immunohistology (Not optimum). Other applications have not been tested. Recommended...

Placental alkaline phosphatase (PLAP) is a membrane bound, zinc-containing metalloenzyme synthesized by syncytiotrophoblast of placenta during the G1 phase of the cell cycle. PLAP is found only in higher primates, and it exhibits a high degree of genetic polymorphism. PLAP consists of 65kD subunit dimers that are...

Four distinct genes encode alkaline phosphatases in humans. The ALPP gene encodes the 67kD placental isozyme, also known as PLAP. In comparison, ALPI, ALPL, and ALPPL2 encode intestinal, liver/bone/kidney, and placental-like or germ cell APs, respectively. The placental alkaline phosphatase is a glycosyl...

Alkaline phosphatase (AP) is a ubiquitously expressed enzyme which removes phosphate groups from target molecules, including DNA, RNA and alkaloids, under alkaline conditions, and is present at higher concentrations in the placenta (placental AP), intestines (intestinal AP) and liver/bone/kidney (tissue non-specific...