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Recombinant Human Calnexin/CANX (C-6His)
Recombinant Human Calnexin/CANX (C-6His)

Item number: ABE-32-9283-50

Source : Human Cells, Protein function: Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the...
Expressed in: Human cells
Origin: human
From 792.00€ *
Review
Desacetyl Bisacodyl
Desacetyl Bisacodyl

Item number: Cay20928-50

Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate. DAB evokes several effects at the colon or rectum, including increased mucus and chloride secretion. Oral administration of bisacodyl leads to decreased expression of aquaporin-3 in the colon of rats. The...
Keywords: DAB, DDPM, 4,4'-(2-pyridinylmethylene)bis-phenol
Application: Bisacodyl metabolite
CAS 603-41-8
MW: 277.3 D
From 38.00€ *
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BX-517
BX-517

Item number: Cay29238-50

BX-517 is an inhibitor of the serine/threonine kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1, IC50 = 6 nM). It binds to the ATP binding pocket of PDK1, inhibits Akt2 activation induced by PDK1 in a cell-free assay (IC50 = 20 nM), and inhibits Akt phosphorylation in PC3 cells.Formal Name:...
Keywords: PDK1 Inhibitor II, N-[2,3-dihydro-2-oxo-3-[1-(1H-pyrrol-2-yl)ethylidene]-1H-indol-5-yl]-urea
Application: PDK1 inhibitor
CAS 850717-64-5
MW: 282.3 D
From 147.00€ *
Review