Source : Human Cells, Protein function: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose...

Menthone is a monoterpene that has been found in A. rugosa and has diverse biological activities. It inhibits the seed germination of R. sativus when used at concentrations of 0.1 and 1 mM. Menthone has insecticidal activity against C. molestus fourth-instar larvae (LC50 = 156 mg/L). It stimulates the proliferation...

PSME3 (Proteasome activator complex subunit 3) belongs to the PA28 family. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave...

Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate. DAB evokes several effects at the colon or rectum, including increased mucus and chloride secretion. Oral administration of bisacodyl leads to decreased expression of aquaporin-3 in the colon of rats. The...