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1 Antikörper Treffer SETD8; histone-lysine N-methyltransferas...
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Name/Antigen KLON WIRT TYP ISOTYP SPEZ. REAKT. FORMAT ANWENDUNG HERSTELLER KAT # MENGE PREIS










Anti-​PR Set7 (SET8, SET Domain Containing 8, SET Domain-​containing Protein 8, SET Domain Containing Lysine Methyltransferase 8, SET Domain-​containing (Lysine Methyltransferase) 8, SETD8, H4 K20 Specific Histone Methyltransferase, H4-​K20-​HMTase SETD8, PR/S
Rabbit
> sec. Ab
Pab
human
Erklärungen der Abkürzungen ansehen.
affinity purified WB
ICCErklärungen der Abkürzungen ansehen.
USBio
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P5575-​01B.100

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100 µl

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667 €
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Anti-PR Set7 (SET8, SET Domain Containing 8, SET Domain-containing Protein 8, SET Domain Containing Lysine Methyltransferase 8, SET Domain-containing (Lysine Methyltransferase) 8, SETD8, H4 K20 Specific Histone Methyltransferase, H4-K20-HMTase SETD8, PR/S


Protein-​lysine N-​methyltransferase that monomethylates both histones and non-​histone proteins. Specifically monomethylates 'Lys-​20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-​382', leading to repress p53/TP53-​target genes. [The UniProt Consortium]
Immunogen: GST-​tagged recombinant protein corresponding to human SETD8 (hPR-​SET7).


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Kat #: P5575-01B.100


Menge:
100 µl

Buy Bulk


Preis:
667 €

UniProt ID: Q9NQR1 (Protein knowledgebase)
Geninformationen: GeneID 387893

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Schlagworte:
Anti-​KMT5A, EC=2.1.1.-​, EC=2.1.1.43, Anti-​PR-​Set7, Anti-​Lysine N-​methyltransferase 5A, Anti-​SET domain-​containing protein 8, Anti-​N-​lysine methyltransferase SETD8, Anti-​PR/SET domain-​containing protein 07, Anti-​Histone-​lysine N-​methyltransferase SETD8, antibody, antibodies, Antikörper

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Products for: SETD8 - histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43]



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