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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
030534.100 | 100 µl | - | - |
3 - 19 business days* |
682.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Platelet-derived growth factor receptor, beta polypeptide, also known as PDGFRB, PDGFRbeta or... more
Product information "Anti-PDGFR"
Platelet-derived growth factor receptor, beta polypeptide, also known as PDGFRB, PDGFRbeta or CD140B. It is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor alpha (PDGFRalpha) and PDGF receptor beta (PDGFRbeta). These growth factors are mitogens for cells of mesenchymal origin. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-PDGFR, Anti-CD140b, Anti-PDGFRB, Anti-PDGFR-1, Anti-PDGFR-beta, EC=2.7.10.1, Anti-PDGF-R-beta, Anti-CD140 antigen-like family member B, Anti-Platelet-derived growth factor receptor 1, Anti-Platelet-derived growth factor receptor beta |
Supplier: | United States Biological |
Supplier-Nr: | 030534 |
Properties
Application: | ELISA, WB |
Antibody Type: | Monoclonal |
Clone: | 13B612 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Purified recombinant fragment of human PDGFR expressed in E. coli. |
Database Information
KEGG ID : | K05089 | Matching products |
UniProt ID : | P09619 | Matching products |
Gene ID | GeneID 5159 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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